Results 111 to 120 of about 5,226,528 (353)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Formalization of Matrix Theory in HOL4

open access: yesAdvances in Mechanical Engineering, 2014
Matrix theory plays an important role in modeling linear systems in engineering and science. To model and analyze the intricate behavior of complex systems, it is imperative to formalize matrix theory in a metalogic setting.
Zhiping Shi   +6 more
doaj   +1 more source

Some Transmuted Software Reliability Models

open access: yesJournal of Mathematical Sciences and Modelling, 2019
The Hausdorff approximation of the shifted Heaviside function $h_{t_0}(t)$ by general transmuted family of cumulative distribution functions is studied and a value for the error of the best approximation is derived in this paper.
Asen Rahnev   +3 more
doaj   +1 more source

Software Reliability in Semantic Web Service Composition Applications [PDF]

open access: yes
Web Service Composition allows the development of easily reconfigurable applications that can be quickly adapted to business changes. Due to the shift in paradigm from traditional systems, new approaches are needed in order to evaluate the reliability of
Andreea DIOSTEANU, Liviu Adrian COTFAS
core   +1 more source

A New Framework and Application of Software Reliability Estimation Based on Fault Detection and Correction Processes

open access: yes, 2015
Software reliability growth modeling plays an important role in software reliability evaluation. To incorporate more information and provide more accurate analysis, modeling software fault detection and correction processes has attracted widespread ...
Xie, Min,   +7 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Optimization of S-N curve fitting based on neighborhood rough set reduction with improved firefly algorithm

open access: yesFracture and Structural Integrity, 2023
S-N curve fatigue samples of titanium alloy welded joints have such a comparatively significant scatter, that results in the issue that the fatigue life prediction accuracy is not optimal.
Yangjinyu Li, Li Zou, Zhengjie Zhu
doaj  

Envelhecimento de software utilizando ensaios de vida acelerados quantitativos [PDF]

open access: yes, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de ProduçãoEste trabalho apresenta uma abordagem sistematizada para acelerar o tempo de vida de sistemas que são acometidos pelos ...
Matias Junior, Rivalino
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy