Results 41 to 50 of about 4,785,942 (298)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2019 Software reliability deals with the probability that software will not cause the failure of a system in a specified time interval. Software reliability growth models (SRGMs) are used to predict future behaviour from known characteristics of software ...
Jabeen, G., +5 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A model driven approach for software systems reliability [PDF]
, 2004 The reliability assurance of software systems from design to deployment level through transformation techniques and model driven approach, is described.
Rodrigues, GN, Emmerich, W, Rosenblum, D
core
Reliability Analysis of Concurrent Systems using LTSA [PDF]
, 2007 The analysis for software dependability is considered an important task within the software engineering life cycle. However, it is often impossible to carry out this task due to the complexity of available tools, lack of expert personnel and time-to ...
David Rosenblum +5 more
core +1 more source
SensorsSpectral chest radiography with photon-counting detectors (PCDs) enables energy-resolved acquisition for bone/soft-tissue separation, but quantitative performance depends on detector cross-talk and the selected material decomposition algorithm.
Sriharsha Marupudi, Bahaa Ghammraoui
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
SOFTWARE RELIABILITY SIMULATION: PROCESS, APPROACHES AND METHODOLOGY [PDF]
, 2011 Reliability is probably the most crucial factor to put ones hand up for in any engineering process. Quantitatively, reliability gives a measure (quantity) of quality, and the quantity can be properly engineered using appropriate reliability engineering ...
Dr.Javaid Iqbal, S.M.K. Quadri
core
Multi-Threshold Corner Detection and Region Matching Algorithm Based on Texture Classification
IEEE Access, 2019 In order to address the unreasonable distributed corners in single threshold Harris detection and expensive computation cost incurred from image region matching performed by normalized cross correlation (NCC) algorithm, multi-threshold corner detection ...
Zetian Tang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source