Results 51 to 60 of about 1,958,921 (299)

Scatter Removal in Photon-Counting Dual-Energy Chest X-Ray Imaging Using a Moving Block Method: A Simulation Phantom Study

Sensors
This work investigates the impact of scatter correction on photon-counting dual-energy chest radiography using a moving block method, focusing on quantifying improvements with the IEC 62220-2-1 dual-energy metrics.
Bahaa Ghammraoui, Yee Lam Elim Thompson
doaj   +1 more source

A model driven approach for software systems reliability [PDF]

, 2004
The reliability assurance of software systems from design to deployment level through transformation techniques and model driven approach, is described.
Emmerich, W, Rodrigues, GN, Rosenblum, D
core  

Supporting software maintenance with non-functional information [PDF]

, 1997
The paper highlights the role of non functional information (about efficiency, reliability and other software attributes) of software components in software maintenance, focusing in the component programming framework.
Botella López, Pere, Franch Gutiérrez, Javier   +1 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Evaluating Machine Learning-Based MRI Reconstruction Using Digital Image Quality Phantoms

Bioengineering
Quantitative and objective evaluation tools are essential for assessing the performance of machine learning (ML)-based magnetic resonance imaging (MRI) reconstruction methods. However, the commonly used fidelity metrics, such as mean squared error (MSE),
Fei Tan, Jana G. Delfino, Rongping Zeng
doaj   +1 more source

Robust Dynamic Selection of Tested Modules in Software Testing for Maximizing Delivered Reliability [PDF]

, 2017
Software testing is aimed to improve the delivered reliability of the users. Delivered reliability is the reliability of using the software after it is delivered to the users. Usually the software consists of many modules. Thus, the delivered reliability
Cai, Kai-Yuan, Cao, Ping, Dong, Zhao, Liu, Ke   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Experimental Study and Rheological Modeling of Water-Based and Oil-Based Drilling Fluids Under Extreme Temperature–Pressure Condition

Energies
With the growing demand for energy, oil and gas exploration and development are progressively moving into deep and ultra-deep formations, where extreme temperatures and pressures create complex challenges for drilling operations.
Haishen Lei, Chun Cai, Baolin Zhang, Jing Luo, Ping Chen, Dong Xiao   +5 more
doaj   +1 more source