Results 51 to 60 of about 163,982 (264)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
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IEEE Access, 2021 Most traditional software reliability growth models (SRGMs) assume immediate fault correction upon detection and therefore only consider fault detection process (FDP).
Kaiye Gao
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
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Bayesian Verification Scheme for Software Reliability Based on Staged Growth Test Information [PDF]
Jisuanji kexueThe prior distribution determination methods of existing Bayesian schemes are relatively conservative and ideal for processing software reliability phased growth testing information.In this article,an edge distribution model for the software success ...
WANG Yuzhuo, LIU Haitao, YUAN Haojie, ZHAI Yali, ZHANG Zhihua
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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Stochastic Formulation of Fault Severity Based Multi Release SRGM Using the Effect of Logistic Learning [PDF]
International Journal of Mathematical, Engineering and Management Sciences, 2017 In today’s environment, software reliability is one of the major concerns for Software firms. Many Software Reliability Growth Model (SRGM) has been developed and many are under process.
Jagvinder Singh +3 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
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A SOFTWARE RELIABILITY GROWTH MODEL FOR VITAL QUALITY METRICS
South African Journal of Industrial Engineering, 2012 <p>ENGLISH ABSTRACTA Non-Homogenous Poisson Process (NHPP) model whose failure intensity function has the same mathematical form as that of a generalized exponential function was proposed for application as a Software Reliability Growth Model (SRGM)
R. Subburaj, G. Gopal, P.K. Kapur
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Modeling Software Reliability with Learning and Fatigue
Mathematics, 2023 Software reliability growth models (SRGMs) based on the non-homogeneous Poisson process have played a significant role in predicting the number of remaining errors in software, enhancing software reliability.
Tahere Yaghoobi, Man-Fai Leung
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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