Results 161 to 170 of about 6,176,166 (267)

Usability and acceptability of four systematic review automation software packages: A mixed method design [PDF]

, 2019
Beller, Elaine, Cleo, Gina, Islam, Farhana, Julien, Blair, Scott, Anna Mae   +4 more
core   +1 more source

AlphaFold Protein Structure Database 2025: a redesigned interface and updated structural coverage. [PDF]

Nucleic Acids Res
Bertoni D, Tsenkov M, Magana P, Nair S, Pidruchna I, Querino Lima Afonso M, Midlik A, Paramval U, Lawal D, Tanweer A, Last M, Patel R, Laydon A, Lasecki D, Dietrich N, Tomlinson H, Žídek A, Green T, Kovalevskiy O, Lau A, Kandathil S, Bordin N, Sillitoe I, Mirdita M, Jones D, Orengo C, Steinegger M, Fleming JR, Velankar S.   +28 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Comparative accuracy of artificial intelligence versus manual interpretation in detecting pulmonary hypertension across chest imaging modalities: a diagnostic test accuracy meta-analysis. [PDF]

Front Artif Intell
Ahmed F, Haider F, Ali R, Arham M, Junaid Y, Dad A, Bakht K, Abbasi M, Malik BT, Mateen A, Gohar N, Ali R, Sattar Y, Ahmed M, Bakr M, Patel S, Almendral J, Alenezi F.   +17 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

MassBank: an open and FAIR mass spectral data resource. [PDF]

Nucleic Acids Res
Neumann S, Meier R, Wenk M, Elapavalore A, Nishioka T, Schulze T, Stravs M, Tsugawa H, Matsuda F, Schymanski EL.   +9 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Review of A-VIEW 3.5 software

Open Praxis, 2013
Mandar Lakshmikant Bhanushe
doaj   +3 more sources

Editorial: Advancing therapeutics for Alzheimer's disease and related dementias through multi-omics data analysis in ethnically diverse populations. [PDF]

Front Mol Neurosci
Garg A, Kumar R, Shrivastava R, Gupta DK, Kumari B, Kumar M.   +5 more
europepmc   +1 more source