Results 61 to 70 of about 1,434,557 (269)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Discussion of Software Testing for Basic Control Software in LKJ System

机车电传动, 2013
Composition of LKJ system and main functions of its basic control software were introduced, as well as the status of software testing for the basic control software.
LONG Hai-quan, HE Xie-zhen, TAN Qi, ZHANG Jia-huan   +3 more
doaj  

3D Face Authentication Software Test Automation

IEEE Access, 2020
The 3D face authentication has become a hot trend for researchers and developers in the recent years, due to its many advantages over the 2D face recognition feature.
Debdeep Banerjee, Kevin Yu
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Field Testing of Software Applications [PDF]

2017 IEEE/ACM 39th International Conference on Software Engineering Companion (ICSE-C), 2017
When interacting with their software systems, users may have to deal with problems like crashes, failures, and program instability. Faulty software running in the field is not only the consequence of ineffective in-house verification and validation techniques, but it is also due to the complexity and diversity of the interactions between an application
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Software Testing: A Changing Career [PDF]

, 2019
The software tester is an imperative component to quality software development. Their role has transformed over the last half a century and volumes of work have documented various approaches, methods, and skillsets to be used in that time. Software projects have gone from using monolithic architectures and heavyweight methodologies, to service-oriented
Cunningham, Sean, Gambo, Jemil, Lawless, Aidan, Moore, Declan, Yilmaz, Murat, Clarke, Paul, O'Connor, Rory   +6 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Model-Based Testing: The New Revolution in Software Testing [PDF]

Database Systems Journal, 2014
The efforts spent on testing are enormous due to the continuing quest for better software quality, and the ever growing complexity of software systems. The situation is aggravated by the fact that the complexity of testing tends to grow faster than the ...
Hitesh KUMAR SHARMA, Sanjeev KUMAR SINGH, Prashant AHLAWAT   +2 more
doaj  

Achieving Successful Software Penetration Testing [PDF]

International Journal of Innovative Solutions in Engineering
In today’s digital environment, where society faces cyber threats, security is a key component of any organization. Penetration testing is crucial in detecting and eliminating security weaknesses before real attackers can use them.
Doris Musa, Ivan Markić
doaj   +1 more source