Results 71 to 80 of about 1,498,468 (269)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Effective Seed Scheduling for Directed Fuzzing with Function Call Sequence Complexity Estimation

open access: yesApplied Sciences
Directed grey-box fuzzers focus on testing specific target code. They have been utilized in various security applications, such as reproducing known crashes and identifying vulnerabilities resulting from incomplete patches.
Xi Peng   +4 more
doaj   +1 more source

Field Testing of Software Applications [PDF]

open access: yes2017 IEEE/ACM 39th International Conference on Software Engineering Companion (ICSE-C), 2017
When interacting with their software systems, users may have to deal with problems like crashes, failures, and program instability. Faulty software running in the field is not only the consequence of ineffective in-house verification and validation techniques, but it is also due to the complexity and diversity of the interactions between an application
openaire   +4 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

AMRerank: A Framework for Library Migration Recommendations Using Multi-Agent Analysis and Data-Driven Reranking

open access: yesIET Software
Open-source libraries are indispensable for modern software development but can create substantial maintenance burdens when they become deprecated or unmaintained.
Jie Luo, Zijie Huang, Jianhua Gao
doaj   +1 more source

Sign Language Recognition Based on CNN-BiLSTM Using RF Signals

open access: yesIEEE Access
As the number of individuals with speech and hearing impairments continues to grow, the demand for sign language recognition systems is increasing. Furthermore, most radio frequency-based gesture recognition systems have primarily focused on simple ...
Yajun Zhang   +5 more
doaj   +1 more source

Testing Concurrent Software [PDF]

open access: yes, 2011
This short two hour tutorial tries to teach practical techniques for testing, review and debugging of concurrent software, based on the Dr. Ur’s research and practical industrial experience in the last ten years.
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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