Results 71 to 80 of about 3,405,045 (356)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Automated System-Level Software Testing of Industrial Networked Embedded Systems [PDF]

arXiv, 2021
Embedded systems are ubiquitous and play critical roles in management systems for industry and transport. Software failures in these domains may lead to loss of production or even loss of life, so the software in these systems needs to be reliable. Software testing is a standard approach for quality assurance of embedded software, and many software ...
arxiv  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Research on Noise Management Technology for Fully Homomorphic Encryption

IEEE Access
Fully homomorphic encryption (FHE) has gradually become an important tool for solving data security and privacy protection issues, because it supports arbitrary computation of encrypted data without the need for prior decryption.
Lifang Bai, Lijuan Bai, Yongjun Li, Zecun Li   +3 more
doaj   +1 more source

Model-Based Testing: The New Revolution in Software Testing [PDF]

Database Systems Journal, 2014
The efforts spent on testing are enormous due to the continuing quest for better software quality, and the ever growing complexity of software systems. The situation is aggravated by the fact that the complexity of testing tends to grow faster than the ...
Hitesh KUMAR SHARMA, Sanjeev KUMAR SINGH, Prashant AHLAWAT   +2 more
doaj  

Studying the Feasibility and Importance of Software Testing: An Analysis [PDF]

IJEST Volume 1 Issue 3 2009 119-128, 2010
Software testing is a critical element of software quality assurance and represents the ultimate review of specification, design and coding. Software testing is the process of testing the functionality and correctness of software by running it. Software testing is usually performed for one of two reasons: defect detection, and reliability estimation ...
arxiv  

Iterative Software Testing

, 1992
Abstract : Software is often developed via a series of modifications and releases. This sort of development implies the testing often takes place in an increasingly familiar structure, rather than a unique or unfamiliar structure. This paper discusses how to exploit this type of development in test planning and execution, by presenting a motivational ...
Shimeall, Timothy, Shimeall, Stephen
openaire   +2 more sources

Software Testing: A Changing Career [PDF]

, 2019
The software tester is an imperative component to quality software development. Their role has transformed over the last half a century and volumes of work have documented various approaches, methods, and skillsets to be used in that time. Software projects have gone from using monolithic architectures and heavyweight methodologies, to service-oriented
Sean Cunningham, Jemil Gambo, Aidan Lawless, Declan Moore, Murat Yilmaz, Paul M. Clarke, Rory V. O’Connor   +6 more
openaire   +4 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source