Results 221 to 230 of about 6,706,538 (285)
microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit +10 more
wiley +1 more source
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source
Some of the next articles are maybe not open access.
ACM SIGSOFT Software Engineering Notes, 1976
Building on the work of others is the only way to make substantial progress in any field. Yet computer programming continues as a cottage industry because programmers insist on reinventing programs for each new application, instead of using what already exists.
Brian W. Kernighan +1 more
openaire +2 more sources
Building on the work of others is the only way to make substantial progress in any field. Yet computer programming continues as a cottage industry because programmers insist on reinventing programs for each new application, instead of using what already exists.
Brian W. Kernighan +1 more
openaire +2 more sources
IEEE Software, 1990
A context is provided for understanding where tools fit in the software life cycle. Tools are divided into vertical and horizontal architectures. Vertical tools support specific activities in a single life-cycle phase, such as analysis, design, or testing.
Dennis B. Smith, Paul W. Oman
openaire +1 more source
A context is provided for understanding where tools fit in the software life cycle. Tools are divided into vertical and horizontal architectures. Vertical tools support specific activities in a single life-cycle phase, such as analysis, design, or testing.
Dennis B. Smith, Paul W. Oman
openaire +1 more source