Results 31 to 40 of about 1,093,401 (218)
New concepts in the design of an IoT electric torque wrench‐based on a smart meter chip
Engineering ReportsElectric torque wrenches play a critical role in the assembly process of high‐strength bolts. This study focuses on three assembly processes for high‐strength bolts and introduces two statistical analysis methods to evaluate the quality of bolt assembly.
Zhaohui Meng +3 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Intuitive Ontology-Based SPARQL Queries for RDF Data Exploration
IEEE Access, 2019 This paper introduces a strategy for both the retrieval and analysis of linked open data (LOD) based on the use of visual tools. Retrieving and understanding data from triplestores (such as SPARQL) requires technical knowledge and proves to be ...
Alejandro Rodriguez Diaz +5 more
doaj +1 more source
A Business Framework of Architecture for a Retail Information System
Problemy Zarządzania, 2022 Purpose: Retail is one of the most important sectors in modern life. Retail information systems support organizational processes in retail chains. Since such systems are very complex, they need to be structured in a framework based on actual business ...
Kateryna Czerniachowska +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
IET Software, 2022 Several operations, ranging from regular code updates to compiling, building, testing, and distribution to customers, are consolidated in continuous integration and delivery.
Azeem Ahmad +2 more
doaj +1 more source
Nanomaterials, 2021 The morphology of nanoparticles governs their properties for a range of important applications. Thus, the ability to statistically correlate this key particle performance parameter is paramount in achieving accurate control of nanoparticle properties ...
Haotian Wen +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Perspectives in Clinical ResearchPrevious articles in this series have looked at various aspects of planning, designing, conducting and interpreting biomedical research. In this article, we offer an overview of some tools and resources available to health and biomedical researchers, to ...
Vishal Deo, Priya Ranganathan
doaj +1 more source