Results 61 to 70 of about 277,049 (293)

Research Progress on Sample Pretreatment Techniques for Alternaria Toxins Residues Analysis in Food

open access: yesLiang you shipin ke-ji
The food infected by Alternaria species can produce Alternaria toxins with genotoxicity, cytotoxicity, reproductive toxicity, and developmental toxicity.
GUAN Wen-bi, MA Jia-li
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Novel Zeolitic Imidazolate Frameworks Based on Magnetic Multiwalled Carbon Nanotubes for Magnetic Solid-Phase Extraction of Organochlorine Pesticides from Agricultural Irrigation Water Samples

open access: yesApplied Sciences, 2018
Magnetic solid-phase extraction is an effective and convenient sample pretreatment technique that has received considerable interest in recent years. A lot of research indicated that magnetic nanocarbon-material-based composites have good application ...
Xiaodong Huang   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Enhancing Analytical Potential for Ultratrace Analysis of Inorganic Oxyanions Using Extraction Procedures with Layered Double Hydroxides

open access: yesToxics
This article provides an overview of the use of layered double hydroxides (LDHs) as effective sorbents in various extraction methods, including column-based solid-phase extraction (SPE), dispersive solid-phase extraction (DSPE), and magnetic solid-phase ...
Ingrid Hagarová, Vasil Andruch
doaj   +1 more source

New trends in sample preparation methods for the determination of flavour compound in beers.

open access: yesKvasný průmysl, 2002
The  most popular  sample preparation  methods for  the determination  of  flavour  compounds  in  beers are usually based  on  steam  distillation  or liquid-liquid extraction.
T. HORÁK   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Silver ion chromatography using solid-phase extraction columns packed with a bonded-sulfonic acid phase.

open access: yesJournal of Lipid Research, 1989
Commercial solid-phase extraction columns packed with a stationary phase with bonded benzenesulfonic acid groups are readily converted to the silver ion form and can then be used for silver ion chromatography of lipids.
W W Christie
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Trends in extraction and purification methods of Lignans in plant-derived foods

open access: yesFood Chemistry: X
Lignans are widely used as dietary supplements within health foods. However, excess addition of lignans can induce adverse reactions, therefore, it is necessary to develop rapid, effective, economical, and environmentally friendly extraction and ...
Yu-tong Yang   +4 more
doaj   +1 more source

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