Results 71 to 80 of about 1,133,928 (295)

Non-diffracting multi-electron vortex beams balancing their electron–electron interactions

Nature Communications, 2017
Vortex electron beams are generated using single electrons but their low beam-density is a limitation in electron microscopy. Here the authors propose a scheme for the realization of non-diffracting electron beams by shaping wavepackets of multiple ...
Maor Mutzafi, Ido Kaminer, Gal Harari, Mordechai Segev   +3 more
doaj   +1 more source

OXIDATION KINETICS OF ALUMINUM ALLOY АЖ2.4М5.3МГ1.1Ц4КР3, ALLOYED WITH TIN, IN SOLID STATE

, 2021
Orif Sh. Davlatov, И. Н. Ганиев, Haydar O. Odinazoda, Safomudin Saydalievich Rajabaliev   +3 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Operation and control of Soft Switching Solid State Transformer as a Virtual Synchronous Machine for Photovoltaic application

, 2022
Vikram Roy Chowdhury, Zheng An, Rajendra Prasad Kandula, Deepak Divan   +3 more
openalex   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Single molecule magnet with an unpaired electron trapped between two lanthanide ions inside a fullerene

Nature Communications, 2017
Single molecule magnets have demonstrated promise for information storage, molecular spintronics and quantum computing, but are limited by their low operational temperatures.
Fupin Liu, Denis S. Krylov, Lukas Spree, Stanislav M. Avdoshenko, Nataliya A. Samoylova, Marco Rosenkranz, Aram Kostanyan, Thomas Greber, Anja U. B. Wolter, Bernd Büchner, Alexey A. Popov   +10 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Preparation, solubility, and anti-inflammatory effects of a complex of diphenylcyclopropenone/β-cyclodextrin derivatives as the treatment of alopecia areata

Journal of Pharmacy & Pharmaceutical Sciences
PurposeTo investigate the preparation of inclusion complexes of diphenylcyclopropenone (DPCP)/β-cyclodextrin (β-CD) derivatives using a three-dimensional (3D) ball mill, and verify the inclusion behavior of the solid dispersion. Additionally, we aimed to
Yutaka Inoue, Kaede Yoshino, Suzu Kudo, Nao Kodama, Hajime Moteki, Mitsutoshi Kimura   +5 more
doaj   +1 more source

High-resolution solid-state NMR of quadrupolar nuclei [PDF]

, 1982
Michael D. Meadows, Karen Smith, Robert A. Kinsey, T. Michael Rothgeb, Robert Skarjune, Eric Oldfield   +5 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source