Results 51 to 60 of about 30,101 (306)

Mechanochemically Induced Solid-State Transformations of Levofloxacin

open access: yesMolecular Pharmaceutics
Levofloxacin hemihydrate (LVXh) is a complex fluoroquinolone drug that exists in both hydrated and anhydrous/dehydrated forms. Due to the complexity of such a compound, the primary aim of this study was to investigate the amorphization capabilities and solid-state transformations of LVXh when exposed to mechanical treatment using ball milling.
Lena Kadri   +4 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

4.5 kW High Frequency Transformer Design for Dual Active Bridge (DAB)

open access: yesJurnal Elkomika
ABSTRAK Indonesia bertujuan untuk beralih dari bahan bakar fosil ke sumber energi terbarukan, dengan target integrasi sebesar 23% pada tahun 2025 dan 31% pada tahun 2050.
NAUFAL HILMI FAUZAN   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Comparison of Isolated DC-DC Converters for Low/Medium Voltage Solid State Transformer applications [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2022
This paper presents a comparative evaluation of isolated dc-dc converter topologies used in Solid State Transformers (SST) meant for low/medium voltage standalone applications.
R B Jeyapradha, V Rajini
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Isolation Transformer for 3-Port 3-Phase Dual-Active Bridge Converters in Medium Voltage Level

open access: yesIEEE Access, 2019
In this paper, an isolation transformer with integrated filter inductances for three-phase three-port dual-active bridge (DAB) converters in the wye-wye-delta (Yyd) configuration is introduced and designed.
Seunghun Baek, Subhashish Bhattacharya
doaj   +1 more source

A Hierarchical Coordinative Control Strategy for Solid State Transformer Based DC Microgrids

open access: yesApplied Sciences, 2020
A solid state transformer (SST), as a kind of energy router in the Energy Internet, provides a unified access point for AC or DC distributed power subjects.
Zheng Li   +3 more
doaj   +1 more source

Resonance analysis of a solid state controlled Tesla transformer

open access: yes, 2011
A Tesla transformer is a source that can generate high voltage with high frequency. It is also known a resonance system becomes two air cored coils.
Halit Taşkin   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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