Results 51 to 60 of about 85,073 (306)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A 2.7-kW, 29-MHz class-E/F/sub odd/ amplifier with a distributed active transformer [PDF]
A Class-E/Fodd high power amplifier (PA) using the distributed active transformer (DAT) is demonstrated at 29MHz. The DAT combines the output power from four VDMOS push-pull pairs.
Jeon, Sanggeun, Rutledge, David B.
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Solid-State Transformers for Interfacing Solar Panels to the Power Grid: An Optimum Design Methodology of a High Frequency Transformer for dc-dc Converter Applications [PDF]
Nowadays the use of power electronic interfaces to integrate distributed generation with the power grid is becoming relevant due to the increased penetration of renewable energy sources like solar, and the continued ...
George, Kenny
core +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Review of Solid-State Transformer Applications on Electric Vehicle DC Ultra-Fast Charging Station
The emergence of DC fast chargers for electric vehicle batteries (EVBs) has prompted the design of ad-hoc microgrids (MGs), in which the use of a solid-state transformer (SST) instead of a low-frequency service transformer can increase the efficiency and
Seyedamin Valedsaravi +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
First Approach for the Modelling of the Electric Field Surrounding a Piezoelectric Transformer in View of Plasma Generation [PDF]
This paper is about an open multi-physics modelling problem resulting from recent investigations into plasma generation by piezoelectric transformers.
Lefèvre, Yvan +2 more
core +2 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

