Results 81 to 90 of about 85,073 (306)
Mechanochemically Induced Solid-State Transformations of Levofloxacin
Molecular PharmaceuticsLevofloxacin hemihydrate (LVXh) is a complex fluoroquinolone drug that exists in both hydrated and anhydrous/ dehydrated forms. Due to the complexity of such a compound, the primary aim of this study was to investigate the amorphization capabilities and solid-state transformations of LVXh when exposed to mechanical treatment using ball milling.
Lena Kadri +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Modeling and Stability Analysis of a Smart Transformer-Fed Grid
IEEE Access, 2020 The interaction of the smart transformer (ST) with the grid-converter-based distributed energy resources (DERs) could trigger instability. Recent research efforts have been made to study the stability issues caused by the resonances (e.g.
Zhixiang Zou +3 more
doaj +1 more source
, 1969 Power control switching circuit using low voltage semiconductor controlled rectifiers for high voltage ...
Herron, B. G.
core +1 more source
Switching frequency optimization for a Solid State Transformer with Energy Storage Capabilities [PDF]
, 2016 Energy Conversion Congress and Exposition (ECCE), 2016 IEEE (2016.
García Fernández, Pablo +4 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
IEEE Access, 2020 Solid-state transformer (SST) is an emerging technology integrating with a transformer power electronics converters and control circuitry. This paper comprehensively reviews the SST topologies suitable for different voltage levels and with varied stages,
Mahammad A. Hannan +6 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A framework for effective management of condition based maintenance programs in the context of industrial development of E-Maintenance strategies [PDF]
, 2016 CBM (Condition Based Maintenance) solutions are increasingly present in industrial systems due to two main circumstances: rapid evolution, without precedents, in the capture and analysis of data and significant cost reduction of supporting ...
Crespo Márquez, Adolfo +3 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source