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3D printing of solid oral dosage forms: numerous challenges with unique opportunities [PDF]

open access: yes, 2020
Since the FDA approval of Spritam, there has been a growing interest in the application of 3D printing in pharmaceutical science. 3D printing is a method of manufacturing involving the layer-by-layer deposition of materials to create a final product ...
ElShaer, Amr   +4 more
core   +1 more source

Insights into solid dosage forms with nonlinear optical imaging

open access: yesJournal of Medical Science, 2023
Microscopic chemical and solid-state structures and their changes in solid drugs and dosage forms can profoundly affect pharmaceutical performance and patient safety.
Teemu Tomberg   +2 more
doaj   +1 more source

X-ray Microtomography as a Non-Invasive Method for Evaluating the Stability of Commercial Effervescent Tablets

open access: yesEngineering Proceedings, 2023
In the present study, a non-invasive X-ray microtomography technique was applied to assess the internal structure of commercial effervescent tablets with vitamin C.
Michał Meisner   +3 more
doaj   +1 more source

Compression Vehicle: A Technical Review

open access: yesGerman Journal of Pharmaceuticals and Biomaterials, 2022
The compressed dosage forms such as tablets are the most preferred and widely accepted due to their dosing accuracy, compactness, manufacturing efficiency, stability and better patient compliance.
Sandesh Somnache   +4 more
doaj   +1 more source

Personalised 3D Printed Medicines: Optimising Material Properties for Successful Passive Diffusion Loading of Filaments for Fused Deposition Modelling of Solid Dosage Forms. [PDF]

open access: yesPharmaceutics, 2020
Although not readily accessible yet to many community and hospital pharmacists, fuse deposition modelling (FDM) is a 3D printing technique that can be used to create a 3D pharmaceutical dosage form by employing drug loaded filaments extruded via a nozzle,
Cerda JR   +9 more
europepmc   +2 more sources

PHARMACEUTICAL DEVELOPMENT: REVIEW OF EQUIPMENT FOR LABORATORY DEVELOPMENT AND PILOT BATCHES PRODUCTION OF SOLID DOSAGE FORMS [PDF]

open access: yesРазработка и регистрация лекарственных средств, 2019
The article summarizes the modern technologies for producing solid dosage forms (SDF). Was presented an overview of technological equipment for laboratory development and pilot batches production of SDF.
N. B. Diomina
doaj   +1 more source

Review: Continuous Manufacturing of Small Molecule Solid Oral Dosage Forms

open access: yesPharmaceutics, 2021
Continuous manufacturing (CM) is defined as a process in which the input material(s) are continuously fed into and transformed, and the processed output materials are continuously removed from the system.
John Wahlich
doaj   +1 more source

A BRIEF REVIEW ON PHARMACEUTICAL DISSOLUTION INTERLINKING THE ASPECTS OF SCIENCE AND REGULATION [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2022
Dissolution is a multistep process describes the affinity of the solute and the solvent by which a solid substance interacts among the heterogeneous phases of solute -solute, solvent-solvent, and the solute-solvent interface to yield a solution.
K Monica   +2 more
doaj   +1 more source

Lubricants in Pharmaceutical Solid Dosage Forms

open access: yesLubricants, 2014
Lubrication plays a key role in successful manufacturing of pharmaceutical solid dosage forms; lubricants are essential ingredients in robust formulations to achieve this.
Jinjiang Li, Yongmei Wu
doaj   +1 more source

Energy efficient smart manufacturing of pharmaceutical solid oral dosage forms

open access: yesJournal of Medical Science, 2023
Background: The global pharmaceuticals market is a trillion-dollar industry which grows more than 5% annually. However, in comparison to other manufacturing industries (e.g., oil refining, automotive), the pharmaceutical sector lags in manufacturing ...
Ashley Dan, Rohit Ramachandran
doaj   +1 more source

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