Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Osmotic dehydration of white cabbage in different hypertonic solutions: Mass transfer kinetics and improvement of nutritional value of the developed product [PDF]
Journal on Processing and Energy in Agriculture, 2013 The presented paper describes an investigation of osmotic dehydration of white cabbage (Brasicca oleracea var. capitata), domestic cultivar Futoški and ways of improving nutritional value of the final product. Osmotic dehydration was carried out in three
Cvetković Biljana +3 more
doaj
Estimates of gains and losses from unmeasured sources and sinks for streamflow and dissolved-solids load in selected reaches of the Arkansas River, southeastern Colorado, 2009-2010 [PDF]
, 2013 Roderick F. Ortiz
openalex +1 more source
Biomolecular solid-state NMR spectroscopy at highest field: the gain in resolution at 1200 MHz [PDF]
, 2021 Morgane Callon +21 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Scientific Reports, 2017 MAS solid-state NMR is capable of determining structures of protonated solid proteins using proton-detected experiments. These experiments are performed at MAS rotation frequency of around 110 kHz, employing 0.5 mg of material.
Kai Xue +8 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
An ultra-high gain and efficient amplifier based on Raman amplification in plasma
Scientific Reports, 2017 Raman amplification arising from the excitation of a density echelon in plasma could lead to amplifiers that significantly exceed current power limits of conventional laser media. Here we show that 1–100 J pump pulses can amplify picojoule seed pulses to
G. Vieux +25 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Ultralow-threshold, continuous-wave upconverting lasing from subwavelength plasmons. [PDF]
, 2019 Miniaturized lasers are an emerging platform for generating coherent light for quantum photonics, in vivo cellular imaging, solid-state lighting and fast three-dimensional sensing in smartphones1-3.
Barnard, Edward S +10 more
core