Results 281 to 290 of about 180,216 (329)
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Current Drug Metabolism, 2020
Background: Solid Lipid Nanoparticles (SLNs) possess unique in vivo features such as high resistivity, bioavailability, and habitation at the target site. Coating nanoparticles with polymers such as chitosan greatly affects their pharmacokinetic behavior, stability, tissue uptake, and controlled drug delivery.
Nasrin Abbasi Gharibkandi +3 more
openaire +2 more sources
Background: Solid Lipid Nanoparticles (SLNs) possess unique in vivo features such as high resistivity, bioavailability, and habitation at the target site. Coating nanoparticles with polymers such as chitosan greatly affects their pharmacokinetic behavior, stability, tissue uptake, and controlled drug delivery.
Nasrin Abbasi Gharibkandi +3 more
openaire +2 more sources
Thymopentin in solid lipid nanoparticles
International Journal of Pharmaceutics, 1996Abstract The pentapeptide thymopentin was englobed in solid lipid nanoparticles prepared from warm microemulsions following two different methods: from O/W microemulsion by forming the more lipophilic ion-pair with hexadecylphosphate, and from W/O/W microemulsion by dissolving the pentapeptide in the aqueous internal phase.
Silvia Morel +3 more
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Solid lipid matrix mediated nanoarchitectonics for improved oral bioavailability of drugs
Expert Opinion on Drug Metabolism & Toxicology, 2019Introduction: Solid matrix mediated lipid nanoparticle formulations (LNFs) retain some of the best features of ideal drug carriers necessary for improving the oral absorption and bioavailability (BA) of both hydrophilic and hydrophobic drugs.
Subhamoy Banerjee, Jonathan Pillai
semanticscholar +1 more source
Oral solid lipid nanoparticle-based antitubercular chemotherapy
Tuberculosis, 2005The present study was planned to evaluate the chemotherapeutic potential of oral solid lipid nanoparticles (SLNs) incorporating rifampicin, isoniazid and pyrazinamide against experimental tuberculosis. The SLNs were prepared by the "emulsion solvent diffusion" technique with an encapsulation efficiency of 51+/-5% for rifampicin, 45+/-4% for isoniazid ...
Rajesh, Pandey +2 more
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Solid lipid nanoparticles Production, characterization and applications
Advanced Drug Delivery Reviews, 2001Solid lipid nanoparticles (SLN) have attracted increasing attention during recent years. This paper presents an overview about the selection of the ingredients, different ways of SLN production and SLN applications. Aspects of SLN stability and possibilities of SLN stabilization by lyophilization and spray drying are discussed.
W, Mehnert, K, Mäder
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Novel Solid Lipid Nanoparticle with Endosomal Escape Function for Oral Delivery of Insulin.
ACS Applied Materials and Interfaces, 2018Yining Xu +5 more
semanticscholar +1 more source