Results 101 to 110 of about 2,897,335 (282)

Preformulation Studies of Intranasal Solid Lipid Nanoparticles of Mometasone Furoate [PDF]

, 2019
The objective of the present work was to prepare intranasal solid lipid nanoparticles (SLN) of mometasone furoate. Mometasone furoate is BCS class II drug having low aqueous solubility and highly sensitive to hepatic metabolism. Mometasone furoate loaded
Amale, Sushant K, Padalkar, Rahul R, Madgulkar, Ashwini R   +2 more
core   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Solid lipid nanoparticles loaded with iron to overcome barriers for treatment of iron deficiency anemia

, 2015
Khaled Mohamed Hosny,1,2 Zainy Mohammed Banjar,3 Amani H Hariri,4 Ali Habiballah Hassan5 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Pharmaceutics and ...
Hosny KM, Hassan AH, Banjar ZM, Hariri AH   +3 more
core  

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Solid lipid nanoparticles in cancer therapy [PDF]

, 2011
The use of solid lipid nanoparticles in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy technology is the latest trend in ...
Rajput, Mithun Singh; College of Pharmacy, IPS Academy, Rajendra Nagar, A.B. Road, Indore- 452012, India, Kumar, Piyush; Niper, ITI Compound, Shri Bhawani Paper Mill Road, Rae Bareli- 229010, India., Shrivastava, Pankaj; Niper, ITI Compound, Shri Bhawani Paper Mill Road, Rae Bareli- 229010, India., Mathur, Vineet; Niper, ITI Compound, Shri Bhawani Paper Mill Road, Rae Bareli- 229010, India., Satrawala, Yamini; Department of Pharmacy, Shri G.S. Institute of Technology and Science 23-Park Road, Indore- 452003, India., Vishvkarma, Akhilesh; Niper, ITI Compound, Shri Bhawani Paper Mill Road, Rae Bareli- 229010, India.   +5 more
core  

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Solid lipid nanoparticles: a new cationic lipid matrix composition for gene transfer,

, 2006
Solid lipid nanoparticles: a new cationic lipid matrix composition for gene ...
FORNI, Flavio, RUOZI, Barbara, VIGHI, Eleonora, BATTINI, Renata, LEO, Eliana Grazia, MONTANARI, Monica   +5 more
core  

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

A REVIEW ON: SOLID LIPID NANOPARTICLES

The ability to incorporate drugs into nanocarriers offers a new prototype in drug delivery that could be used for secondary and tertiary levels of drug targeting. Hence, solid lipid nanoparticles hold great promise for reaching the goal of controlled and site specific drug delivery and hence have attracted wide attention of researchers.
  +5 more sources

Solid lipid nanoparticle a complete tool for brain targeted drug delivery

Current Issues in Pharmacy and Medical Sciences
The current review focuses on the potential of solid lipid nanoparticulate systems for effective targeted delivery to the brain. The challenges in delivering the drug to the brain are discussed, as are brain targeting strategies and possible mechanisms.
Parthiban Ramalingam, Gouranga Dutta, Mothilal Mohan, Abimanyu Sugumaran   +3 more
doaj   +1 more source