Results 121 to 130 of about 114,436 (357)

Solid Lipid Nanoparticles for Dibucaine Sustained Release

open access: yesPharmaceutics, 2018
Dibucaine (DBC) is among the more potent long-acting local anesthetics (LA), and it is also one of the most toxic. Over the last decades, solid lipid nanoparticles (SLN) have been developed as promising carriers for drug delivery.
Raquel de M. Barbosa   +8 more
doaj   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Solid lipid nanoparticles for ocular drug delivery

open access: yesDrug Delivery, 2010
Ocular drug delivery remains challenging because of the complex nature and structure of the eye. Conventional systems, such as eye drops and ointments, are inefficient, whereas systemic administration requires high doses resulting in significant toxicity.
Ali, Seyfoddin   +2 more
openaire   +2 more sources

Green Solid Lipid Nanoparticles by Fatty Acid Coacervation: An Innovative Nasal Delivery Tool for Drugs Targeting Cerebrovascular and Neurological Diseases

open access: yesPharmaceutics
Cerebrovascular and neurological diseases are characterized by neuroinflammation, which alters the neurovascular unit, whose interaction with the choroid plexus is critical for maintaining brain homeostasis and producing cerebrospinal fluid. Dysfunctions
Annalisa Bozza   +13 more
doaj   +1 more source

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

open access: yesBeilstein Journal of Nanotechnology, 2019
This investigation is a study of new lipid nanoparticles for cutaneous antioxidant delivery. Several molecules, such as α-tocopherol and retinoic acid, have been shown to improve skin condition and even counteract the effects of exogenous stress factors ...
Elisabetta Esposito   +7 more
doaj   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni   +11 more
wiley   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans   +11 more
wiley   +1 more source

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