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Solid Lipid Nanoparticles for Drug Delivery
2023Solid lipid nanoparticles are promising carriers that allow for the delivery of poorly water-soluble drugs and have the potential to achieve sustained drug release or targeted delivery to the site of interest. Here we describe the preparation of solid lipid nanoparticles by forming a microemulsion at an elevated temperature which, upon cooling, yields ...
Wei-Chung, Luo, Xiuling, Lu
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In vitro biocompatibility of solid lipid nanoparticles
Science of The Total Environment, 2012This study was undertaken to address the current deficient knowledge of cellular response to solid lipid nanoparticles (SLNs) exposure. We investigated the cytotoxicity of several SLNs formulations in two fibroblast cell lineages, Vero and MDCK. Several methods were used to explore the mechanisms involved in this cytotoxic process, including cell ...
Adny Henrique, Silva +4 more
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Current Drug Delivery, 2008
The first generation of solid lipid carrier systems in nanometer range, Solid Lipid Nanoparticles (SLN), was introduced as an alternative to liposomes. SLN are aqueous colloidal dispersions, the matrix of which comprises of solid biodegradable lipids.
S S, Shidhaye +4 more
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The first generation of solid lipid carrier systems in nanometer range, Solid Lipid Nanoparticles (SLN), was introduced as an alternative to liposomes. SLN are aqueous colloidal dispersions, the matrix of which comprises of solid biodegradable lipids.
S S, Shidhaye +4 more
openaire +2 more sources
2006
In the last decade of the last century, solid lipid nanoparticles (SLN) have been introduced to the literature as a novel carrier system for cosmetic active ingredients and pharmaceutical drugs. SLN consist of biodegradable physiological lipids or lipidic substances and stabilisers which are generally recognised as safe (GRAS) or have a regulatory ...
Anne Saupe, Thomas Rades
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In the last decade of the last century, solid lipid nanoparticles (SLN) have been introduced to the literature as a novel carrier system for cosmetic active ingredients and pharmaceutical drugs. SLN consist of biodegradable physiological lipids or lipidic substances and stabilisers which are generally recognised as safe (GRAS) or have a regulatory ...
Anne Saupe, Thomas Rades
openaire +1 more source
A Review on Solid Lipid Nanoparticle
Research Journal of Pharmaceutical Dosage Forms and Technology, 2016Solid lipid nanoparticles (SLN) are the emerging field of nanotechnology having many potential applications in drug delivery as well as in research. Lipid nanoparticles offer possibility to develop new therapeutics due to their unique size dependent properties.
Amol M Patil +4 more
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Clinical Utility of Solid Tumor Epigenetics
Medical Epigenetics, 2021Sevin Turcan, Julian Taranda
exaly