Results 71 to 80 of about 4,672,322 (298)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Phase separation in solid solution upon cooling: vial projection
, 2010 The vial containing a mixture of cyclohexane and aniline cooling from 35°, has been filmed perpendicular to the direction of the laser light (left to right). When the critical temperature is reached and the mixture goes from a single phase to two phases,
DoITPoMS, University of Cambridge
core
Characterization of synthetic hedenbergite (CaFeSi2O6)–petedunnite (CaZnSi2O6) solid solution series by X-ray single crystal diffraction [PDF]
Clinopyroxenes along the solid solution series hedenbergite (CaFeSi2O6)-petedunnite (CaZnSi2O6) were synthesized under hydrothermal conditions and different oxygen fugacities at temperatures of 700 to 1200 °C and pressures of 0.2 to 2.5 GPa.
Bromiley, G. D. +4 more
core +1 more source
ELECTROPHYSICAL MEASUREMENTS SOLID SOLUTIONS OF InxAl1–xAs
Конденсированные среды и межфазные границы, 2019 Purpose. Layers of InxAl1-xAs, grown at the Novosibirsk Institute of Semiconductor Physics of the Siberian Branch of the Russian Academy of Science that are deliberately unalloyed by means of the MBE method on a semi-insulating substrate InP are widely ...
Mikhailyuk Ekaterina A. +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Phase separation in solid solution upon cooling: laser beam projection
, 2010 As video 58, but filmed looking into the laser light after it has passed through the vial (i.e. the video is of the laser beam as projected onto a screen): The vial contains a mixture of cyclohexane and aniline cooling from 35°.
DoITPoMS, University of Cambridge
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Superprotonic Solid Acids: Thermochemistry, Structure, and Conductivity [PDF]
, 2013 In this work, in order to investigate the thermochemistry and property of the superprotonic solid acid compounds, the measurement methods were established for in situ observation, because superprotonic phases are neither stable at room temperature nor ...
Ikeda, Ayako
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Solid Solutions LnxU1−xC2 with Ln = Tb, Dy, Ho, Tm, and Lu Showing Ideal Vegard Behavior
, 2023 The reaction of UO2 with the respective lanthanide metal and purified graphite in an arc-melting furnace led to the formation of solid solutions of the composition LnxU1−xC2, with Ln = Tb, Dy, Ho, Tm, and Lu.
Uwe Ruschewitz +2 more
core +1 more source