Results 61 to 70 of about 492,364 (268)

Discrete modeling of ionic space charge zones in solids

Physical Chemistry Chemical Physics, 2022
Discretization allows not only for a realistic treatment of space charge layers in solids but also for a straightforward incorporation of non-idealities.
Chuanlian Xiao, Chia-Chin Chen, Joachim Maier   +2 more
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Cascaded chiral birefringent media enabled planar lens with programable chromatic aberration

PhotoniX
Wavefront control is the fundamental requirement in optical informatics. Planar optics have drawn intensive attention due to the merits of compactness and light weight.
Dewei Zhang, Chun-Ting Xu, Quan-Ming Chen, Han Cao, Hong-Guan Yu, Qing-Gui Tan, Yan-qing Lu, Wei Hu   +7 more
doaj   +1 more source

Designing Efficient Spaced Seeds for SOLiD Read Mapping [PDF]

Advances in Bioinformatics, 2010
The advent of high-throughput sequencing technologies constituted a major advance in genomic studies, offering new prospects in a wide range of applications.We propose a rigorous and flexible algorithmic solution to mapping SOLiD color-space reads to a reference genome.
Noé, Laurent, Gîrdea, Marta, Kucherov, Gregory   +2 more
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

New CAD modeling approach in Geant4 with half-space CSG

Frontiers in Nuclear Engineering
Geant4 offers constructive solid geometry (CSG) for modeling detector geometries, but representing intricate computer-aided design (CAD) structures can be cumbersome. This article presents a novel approach that overcomes this limitation.
Y. Qiu
doaj   +1 more source

Dense Packing of Space with Various Convex Solids [PDF]

, 2013
One of the basic problems in discrete geometry is to determine the most efficient packing of congruent replicas of a given convex set $K$ in the plane or in space. The most commonly used measure of efficiency is density. Several types of the problem arise depending on the type of isometries allowed for the packing: packing by translates, lattice ...
Bezdek, András, Kuperberg, Włodzimierz
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

FROM SOLID SPACES TO LIQUID SPACES: NEW ECOLOGIES OF MUSICAL PRACTICES

Humanities & Social Sciences Reviews, 2019
Purpose: In recent years, the interest in creating new educational spaces has increased substantially, aiming to influence the methods of learning of our students and to adopt new educational strategies. This article highlights the importance of the atmosphere when remodeling musical practices.
Murillo Ribes, Adolf, Riaño Galán, María Elena, Berbel Gómez, Noemy   +2 more
openaire   +4 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source