Results 51 to 60 of about 646,561 (358)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Comparing the effects of two different vitamin regimens on bone metabolism for meat ducks at starting phase

Italian Journal of Animal Science
Objective Leg problems including lameness and tibial dyschondroplasia (TD) are one of the most important factors affecting health and animal welfare in meat-type poultry, which are considerably impacted by dietary vitamin regimens.
Ling Zhou, Pinyao Zhao, Yan Liu, Wei Zhao, Anran Jiao   +4 more
doaj   +1 more source

Enzyme production by solid-state fermentation [PDF]

, 2009
Solid-state fermentation (SSF) is a fermentation process which uses moist solid supports (mainly, agro-industrial residues) as substrate. This process has many advantages when compared with submerged fermentation (SmF) and is being successfully ...
Abrunhosa, Luís, Teixeira, J. A., Venâncio, Armando   +2 more
core  

Dietary bioactive lipid compounds rich in menthol alter Interactions among members of ruminal microbiota in sheep [PDF]

, 2019
This study aimed to investigate the effects of two practically relevant doses of menthol-rich plant bioactive lipid compounds (PBLC) on fermentation, microbial community composition, and their interactions in sheep rumen.
Aschenbach, Jörg R., Braun, Hannah-Sophie, Geiger, Sebastian, Park, Tansol, Patra, Amlan K., Pieper, Robert, Yu, Zhongtang   +6 more
core   +1 more source

Application of Wickerhamomyces anomalus in Simulated Solid-State Fermentation for Baijiu Production: Changes of Microbial Community Structure and Flavor Metabolism

Frontiers in Microbiology, 2020
Wickerhamomyces anomalus is conducive to the synthesis of ester compounds in brewing the Chinese liquor Baijiu; esters are crucial for the quality of Baijiu.
Wenhua Wang, Guangsen Fan, Xiuting Li, Zhilei Fu, Xin Liang, Baoguo Sun   +5 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Prokaryotic evolution shapes specialized communities in long term engineered pit mud ecosystem

npj Biofilms and Microbiomes
Elucidating the temporal dynamics of complex microbial consortia is crucial for engineering robust microbiome. We investigated prokaryotic evolution in pit mud, a centuries-old engineered environment used in Chinese liquor fermentation.
Yan Zeng, Xiaozhong Zhong, Lijuan Chai, Xiaojuan Zhang, Zhenming Lu, Guangqian Liu, Tingyao Tu, Lingfei Lu, Rui Zhang, Hui Yu, Suyi Zhang, Songtao Wang, Caihong Shen, Jinsong Shi, Zhenghong Xu   +14 more
doaj   +1 more source

Antioxidant Profile and Biosafety of White Truffle Mycelial Products Obtained by Solid-State Fermentation

Molecules, 2021
Solid-state fermentation may produce therapeutic compounds with higher biomass or better product characteristics than those generated by submerged fermentation.
Jui-Yi Hsu, Ming-Hsuan Chen, Yu-Shen Lai, Su-Der Chen   +3 more
doaj   +1 more source

The effects of solid-state fermentation on the content, composition and in vitro antioxidant activity of flavonoids from dandelion

PLoS ONE, 2020
Dandelion (Taraxacum officinale), a common plant worldwide, is used as both a medicine and food. Fermentation is a food processing technology that has many advantages, such as low energy cost, changes in product characteristics, and enhanced product ...
N. Liu, Min Song, Naifeng Wang, Yuan-Chen Wang, Ruifang Wang, X. An, J. Qi   +6 more
semanticscholar   +1 more source