Results 51 to 60 of about 634,574 (311)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Enhanced nutritional value of chickpea protein concentrate by dry separation and solid state fermentation

, 2020
A sustainable dry processing method to obtain nutritional and functional chickpea products was developed, yielding protein concentrates suited to prepare products without additives.
Qinhui Xing, S. Dekker, K. Kyriakopoulou, R. Boom, E. Smid, M. Schutyser   +5 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research progress of solid-state pure culture equipment and technology [PDF]

Zhongguo niangzao
Solid-state pure culture is a biotechnology that simulates the natural fermentation environment. It uses solid matrix such as rice, bran, soybean meal as the growth medium for industrial microorganisms to ferment and produce by single microbial strain ...
TAI Yanxiang, YANG Wen, LIU Huipeng, HONG Housheng
doaj   +1 more source

Variations of Soybean Meal and Corn Mixed Substrates in Physicochemical Characteristics and Microbiota During Two-Stage Solid-State Fermentation

Frontiers in Microbiology, 2021
Corn germ meal (CGM) and corn gluten feed (CGF) are the two main corn byproducts (CBs) obtained from corn starch extraction. Due to their high fiber content, low protein content, and severe imbalance of amino acid, CBs are unable to be fully utilized by ...
Weifa Su, Zipeng Jiang, Lihong Hao, Wentao Li, Tao Gong, Yu Zhang, S. Du, Cheng Wang, Zeqing Lu, Mingliang Jin, Yizhen Wang   +10 more
semanticscholar   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Contribution of Debaryomyces hansenii to Microbial, Lipidome, and Flavor Properties of Sichuan Bacon

Fermentation
Debaryomyces hansenii has the potential to enhance the flavor profile of traditional fermented meat products. This study investigates the impact of the D. hansenii LY090 strain on the microbial community, lipidome, flavor profiles, and sensory properties
Song Wang, Kaidi Hu, Wanshu Pan, Ling You, Yong Yang, Shuliang Liu   +5 more
doaj   +1 more source

Research Progress on Monitoring and Regulation of Closed Solid-State Fermentation Systems [PDF]

Shipin Kexue
A closed solid-state fermentation system refers to a system that automatically and intelligently completes solid-state fermentation under closed and controllable conditions to stabilize product quality, reduce labor intensity and improve intelligence ...
ZHANG Nan, CHENG Siyuan, YU Yongjian, DOU Shuaiwei, LIU Jiaxin, TANG Ruijun, ZHU Yuanyuan, YU Zhen
doaj   +1 more source

Antioxidant Profile and Biosafety of White Truffle Mycelial Products Obtained by Solid-State Fermentation

Molecules, 2021
Solid-state fermentation may produce therapeutic compounds with higher biomass or better product characteristics than those generated by submerged fermentation.
Jui-Yi Hsu, Ming-Hsuan Chen, Yu-Shen Lai, Su-Der Chen   +3 more
doaj   +1 more source

Physicochemical Factors Affecting Microbiota Dynamics During Traditional Solid-State Fermentation of Chinese Strong-Flavor Baijiu

Frontiers in Microbiology, 2020
Spontaneous solid-state fermentation (SSF) of Chinese Baijiu involves diverse microbes from Daqu and pit mud (PM). Given that the transfer of interphase microflora during the fermentation is a continuous and dynamic process, longitudinal studies are ...
Tong-wei Guan, Yijin Lin, Kebao Chen, Meng-ying Ou, Jiaxu Zhang   +4 more
semanticscholar   +1 more source