Results 81 to 90 of about 19,360,112 (295)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Mini-LED and Micro-LED: Promising Candidates for the Next Generation Display Technology

open access: yesApplied Sciences, 2018
Displays based on inorganic light-emitting diodes (LED) are considered as the most promising one among the display technologies for the next-generation.
Tingzhu Wu   +9 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Light-Emitting Diodes in the Solid-State Lighting Systems [PDF]

open access: yes, 2014
Red and green light-emitting diodes (LEDs) had been produced for several decades before blue emitting diodes, suitable for lighting applications, were widely available.
Sparavigna, Amelia Carolina   +1 more
core   +1 more source

Improvements on Remote Diffuser-Phosphor-Packaged Light-Emitting Diode Systems

open access: yesIEEE Photonics Journal, 2014
By modifying traditional remote phosphor-diffuser-packaged light-emitting diode systems, we have managed to increase the luminous efficacy from 145.7 to 162.3 lm/W.
Hua Xiao   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Energy efficient innovative lighting and energy supply solutions in developing countries [PDF]

open access: yes, 2007
The vast majority of the rural population in the de veloping countries is out of reach of electricity and hence has to depend on the tradi tional fuels to fulfil the daily energy needs.
Halonen, L.   +3 more
core  

Solid-state lighting - a benevolent technology

open access: yes, 2018
Solid-state light sources are in the process of profoundly changing the way humans generate light for general lighting applications. Solid-state light sources possess two highly desirable features, which set them apart from most other light sources: ( i)
Kim, JK, Schubert, EF, Luo, H, Xi, JQ
core   +1 more source

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