Results 271 to 280 of about 8,266,387 (310)

Antibody-Radionuclide Conjugates for Solid Tumors: Multidimensional Strategies from Component Engineering to Synergistic Combination Therapy. [PDF]

Int J Mol Sci
Zhao M, Zhao X, Gao Z, Shao R, Liu L, Zhao W.   +5 more
europepmc   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

Phase I Study of Rogocekib in Patients with Advanced, Relapsed, or Refractory Malignant Solid Tumors. [PDF]

Clin Cancer Res
Sato J, Katsuya Y, Koyama T, Shimizu T, Tanoue Y, Yamamoto M, Tozaki H, Takahara E, Shoji S, Mizutani A, Morishita D, Oda RW, Miyake H, Yonemori K, Yamamoto N.   +14 more
europepmc   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

A spatially resolved implantable microdevice for multiplexed in situ screening of engineered cellular therapies in solid tumors. [PDF]

Sci Adv
Panikkanvalappil SR, Maloney E, Ahn SW, Martin S, Marlin C, Bhagavatula SK, Jonas O.   +6 more
europepmc   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

CAR-T and TIL therapies in solid tumors: barriers, clinical lessons, and convergent solutions. [PDF]

Cancer Cell Int
Bach DH, Hoang VT, Huong PTV, Nguyen DD, Nguyen TL.   +4 more
europepmc   +1 more source

Clinical evidence on non-viral CAR-T cell therapies for solid tumors: a scoping review. [PDF]

Front Immunol
Varón Suárez F, Moreno J, Arias-Valderrama O, Baena J.   +3 more
europepmc   +1 more source

Ceralasertib Plus Durvalumab in Chinese Patients with Advanced Solid Tumors: A Nonrandomized Clinical Trial. [PDF]

Oncol Ther
Sun Y, Zhong J, Sun H, Parr G, Lukacs E, Slade D, Zhou Y, Ren X, Kirk D, Kmieciak A, Yao T, Wang J.   +11 more
europepmc   +1 more source

Publisher Correction: Ceralasertib Plus Durvalumab in Chinese Patients with Advanced Solid Tumors: A Nonrandomized Clinical Trial. [PDF]

Oncol Ther
Sun Y, Zhong J, Sun H, Parr G, Lukacs E, Slade D, Zhou Y, Ren X, Kirk D, Kmieciak A, Yao T, Wang J.   +11 more
europepmc   +1 more source