Results 131 to 140 of about 457,366 (268)

Landscape of T-cell engagers in solid tumors. [PDF]

Oncologist
Garcia-Lorenzo E, Dorta M, Doger B, Pedregal M, Moreno V.   +4 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Utility of Ultra-Low-Pass Whole Genome Sequencing in Bile CfDNA for the Management of Patients With Biliary Strictures

The Journal of Liquid Biopsy, 2023
M. Arechederra, C. Rojo, M. Rullán, M. Elizalde, J. Herranz, D. Oyón, J. Argemí, J. Urman, M. Ávila, C. Berasain   +9 more
doaj   +1 more source

CAR-M Therapy: From Concept to Clinical Translation in Solid Tumors. [PDF]

Cells
Miao C, Chen Z, Chen J, Sun J, Sun Y, Shi W, Xu W, Li Y, Zhao X.   +8 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

NN-01-195, a Novel Conjugate of HSP90 and AURKA Inhibitors, Effectively Targets Solid Tumors. [PDF]

Mol Cancer Ther
Nguyen TT, Nandwana NK, Srikanth YVV, Bagnyukova T, Chkhalo O, Cai KQ, Lamperelli J, Pirestani S, Mehra MK, Burtness BA, Borghaei H, Akunuri R, Cassel J, Lu L, Salvino JM, Golemis EA.   +15 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

A new perspective on immune evasion: escaping immune surveillance by inactivating tumor suppressors

Signal Transduction and Targeted Therapy, 2022
Svenja Mergener, Samuel Peña-Llopis
doaj   +1 more source

Generation of functional canine TIL products for solid tumors. [PDF]

Front Immunol
Foos KM, Pandey V, Jennings MW, Powell DJ, Mason NJ.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source