Results 151 to 160 of about 720,989 (310)

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source

Utility of Ultra-Low-Pass Whole Genome Sequencing in Bile CfDNA for the Management of Patients With Biliary Strictures

The Journal of Liquid Biopsy, 2023
M. Arechederra, C. Rojo, M. Rullán, M. Elizalde, J. Herranz, D. Oyón, J. Argemí, J. Urman, M. Ávila, C. Berasain   +9 more
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Obstacles and improvement strategies for CAR-T cell therapy in solid tumors. [PDF]

Discov Oncol
Luo Z, Hu Q, Ren M, Wang L, Zou Q, Wen X, Chen S, Liu Q, Luo D, Guo Z.   +9 more
europepmc   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Minimal residual disease in solid tumors: Clinical applications and future directions. [PDF]

Cancer
Abdo T, Alhalabi A, Yaghi S, Aloran M, Li Y, Herrán M, Tfayli R, Samuel TA, Nahleh Z.   +8 more
europepmc   +1 more source

A new perspective on immune evasion: escaping immune surveillance by inactivating tumor suppressors

Signal Transduction and Targeted Therapy, 2022
Svenja Mergener, Samuel Peña-Llopis
doaj   +1 more source

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Correlation of Cell-in-Cell Structure With Prognosis in Solid Tumors-A Meta-Analysis. [PDF]

Biomed Res Int
Zi H, Dai Y, Li M, Wang Y, Wang M, Wang S, Bai Y, Sun J, Fan C, Ding J, Wang T.   +10 more
europepmc   +1 more source