Results 241 to 250 of about 2,792,307 (313)

Overcoming Barriers in Solid Tumors: Lactate-Fueled Nanomotors Enhance Penetration and Reverse Immunosuppression. [PDF]

J Am Chem Soc
Esteve-Moreno JJ, Escudero A, Hicke FJ, Sanz-Álvarez V, Miralles-Buleo M, Marcos MD, Martínez-Bisbal MC, García-Fernández A, Díez P, Martínez-Máñez R.   +9 more
europepmc   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Bioengineered cell therapies for pediatric solid tumors: unmet needs and a measurement-integrated approach. [PDF]

Prog Biomed Eng (Bristol)
Sandoval-Castellanos AM, Ahn YR, Canter RJ, Brown EG, Kim J.   +4 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Correction: Beyond boundaries: exploring the role of extracellular vesicles in organ-specific metastasis in solid tumors. [PDF]

Front Immunol
Nidhi G, Yadav V, Singh T, Sharma D, Bohot M, Satapathy SR.   +5 more
europepmc   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

Case Report: Primed dendritic cell immunotherapy for multiple solid tumors. [PDF]

Front Immunol
Jones J, Alrabaa A, Decker W, Ferbeyre L, Viramontes G, Gonzalez R, Angulo E, Zamudio A, Hernandez R, Noga S, Hernandez-Reyes S, Zhang P, Smith D, Karamanian A, Tamara L, Greenwood D, Halpert M.   +16 more
europepmc   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

CEACAM5-Targeted Therapies in Solid Tumors: Biological Barriers and Next-Generation Precision Strategies. [PDF]

Drug Des Devel Ther
Ye T, Mei R, Liu X, Huang P.
europepmc   +1 more source