Results 131 to 140 of about 456,407 (268)

Targeting Bruton’s Tyrosine Kinase (BTK) in Autoimmunity: Achievements, Opportunities and Challenges

open access: yesDrug Design, Development and Therapy
Sebastian Torke,1,* Sarah Dybowski,2,* Martin S Weber2– 41Experimental and Clinical Research Center, Charité-Medical Center Berlin and Max-Delbrück-Center for Molecular Medicine, Berlin, Germany; 2Department of Neurology, University ...
Torke S, Dybowski S, Weber MS
doaj  

Plying potency assays for immunotherapy of solid tumors. [PDF]

open access: yesFront Immunol
Burns JS, Gjeta R, Lesný P, Vives J.
europepmc   +1 more source

A Bioinspired Sensory‐CAPode With Dual Functionality: Logic Gate and Real‐Time Biosensing

open access: yesAdvanced Functional Materials, EarlyView.
An electrochemical capacitor diode (CAPode) redefines the frontier of iontronics by seamlessly unifying logic computing and biosensing within a single biocompatible platform. Inspired by nature's own ion‐channel circuitry, this elegant ionic system transforms complex chemical signals into precise electrical responses, paving the way for next‐generation
Hanfeng Zhou   +10 more
wiley   +1 more source

Clinical application and optimization strategies for antibody-drug conjugates in solid tumors. [PDF]

open access: yesJ Int Med Res
Qu J   +7 more
europepmc   +1 more source

Three‐Dimensional Biomimetic Aerogel Conduits with Electro‐Ionic‐Immune Coupling Reverse the Pathological Cascade of Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu   +9 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Retraction Note: Hurdles to breakthrough in CAR T cell therapy of solid tumors. [PDF]

open access: yesStem Cell Res Ther
Marofi F   +11 more
europepmc   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

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