Results 31 to 40 of about 755,181 (358)

Interventional oncology: A primer for clinicians on the role of ablation and embolization for solid tumors. [PDF]

open access: yesCA Cancer J Clin
Abdelsalam ME   +9 more
europepmc   +2 more sources

Circulating tumor DNA reveals complex biological features with clinical relevance in metastatic breast cancer

open access: yesNature Communications, 2023
Plasma ctDNA is a promising method to determine patient outcome in multiple cancer types. Here, the authors use shallow WGS to create machine learning signatures to identify tumor phenotypes and predict therapy response in patients with metastatic breast
Aleix Prat   +31 more
doaj   +1 more source

The influence of anisotropic growth and geometry on the stress of solid tumors [PDF]

open access: yes, 2017
Solid stresses can affect tumor patho-physiology in at least two ways: directly, by compressing cancer and stromal cells, and indirectly, by deforming blood and lymphatic vessels.
Bravo-Castillero, Julián   +9 more
core   +1 more source

FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis

open access: yesJournal of Translational Medicine
Background Acute pancreatitis (AP) presents a significant clinical challenge with limited therapeutic options. The complex etiology and pathophysiology of AP emphasize the need for innovative treatments.
Amaya Lopez-Pascual   +18 more
doaj   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

Wilms\u27 Tumor and Neuroblastom: Results of Therapy [PDF]

open access: yes, 1973
Wilms\u27 tumor and neuroblastoma are numerically among the most common noncerebral malignant solid tumors in children.
Maurer, Harold M.
core   +1 more source

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost   +10 more
wiley   +1 more source

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer [PDF]

open access: yes, 2014
The underpinnings of STAT3 hyperphosphorylation resulting in enhanced signaling and cancer progression are incompletely understood. Loss-of-function mutations of enzymes that dephosphorylate STAT3, such as receptor protein tyrosine phosphatases, which ...
Bahar, Ivet   +21 more
core   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell   +3 more
wiley   +1 more source

Adenoid cystic carcinoma: emerging role of translocations and gene fusions. [PDF]

open access: yes, 2016
Adenoid cystic carcinoma (ACC), the second most common salivary gland malignancy, is notorious for poor prognosis, which reflects the propensity of ACC to progress to clinically advanced metastatic disease.
Brait, Mariana   +5 more
core   +7 more sources

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