Results 141 to 150 of about 108,716 (266)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Inferring the development of microsegregation and microstructure in Spheroidal and Compacted Graphite Iron using EPMA‐WDS

, 2017
Microsegregation is closely related to the solidification characteristics and microstructure development of a material. In this paper, the microsegregation of Si, Cu, Mn, and P was investigated on a spheroidal and a compacted graphite iron using a ...
Diószegi, Attila, Domeij, Björn
core  

Laser Additively Manufactured High-Entropy Alloys via Laser Powder Bed Fusion and Laser-Directed Energy Deposition: Process-Structure-Property Relationships and Design Strategies. [PDF]

Materials (Basel)
Lee MY, Kim HS, Yeh AC.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Microstructural Evolution and Mechanical Properties of AA2017 Aluminum Alloy Joints Produced by Rotary Friction Welding and TIG Welding. [PDF]

Materials (Basel)
Noga P, Kula A, Wiewióra M, Skrzekut T.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Author Correction: Segregation-dislocation self-organized structures ductilize a work-hardened medium entropy alloy

Nature Communications
Bojing Guo, Dingcong Cui, Qingfeng Wu, Yuemin Ma, Daixiu Wei, Kumara L. S. R, Yashan Zhang, Chenbo Xu, Zhijun Wang, Junjie Li, Xin Lin, Jincheng Wang, Xun-li Wang, Feng He   +13 more
doaj   +1 more source

Scandium Microalloying for Al-Cu-Mg-Mn-Ti Alloys with High Cu Content. [PDF]

Materials (Basel)
Guo J, Dong H, Wang Y, Wang Y, Zhao Z, Zhang R, Li Z, Liang Y, Yang Z.   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Impact of adsorption-based solidification on the pharmaceutical performance and antidyslipidemic efficacy of simvastatin-ezetimibe SNEDDS. [PDF]

Int J Pharm X
Priani SE, Sopyan I, Chaerunisaa AY, Wilar G.   +3 more
europepmc   +1 more source