Results 71 to 80 of about 2,076,289 (344)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Unravel melt pool and bubble dynamics during laser powder bed fusion of polyamides using synchrotron X-ray imaging and process simulation

Virtual and Physical Prototyping
Laser powder bed fusion (LPBF) of Polyamide 12 (PA12) using a near-infra-red (NIR) beam is largely unexplored; therefore, the beam-matter interaction, evolution mechanisms of the melt pool and defects remain unclear. Here, we employed a combination of in
Chu Lun Alex Leung, Jabbar Gardy, Mark Isaacs, Shashidhara Marathe, Michał M. Kłosowski, Junji Shinjo, Chinnapat Panwisawas, Peter D. Lee   +7 more
doaj   +1 more source

Bimodal distribution of the solid products in a magmatic chamber: Modelling by fractional crystallization and coupling of the chemical exchanges with the differential melt/solid transport ================================================ Répartition bimodale des produits solides d'une chambre magmatique : modélisation par cristallisation fractionnée avec couplage des échanges chimiques et du transport différentiel magma/solide [PDF]

, 2010
International audienceOur aim is to explain the possible bimodality of the compositions of the magmatic rocks of the same province. In order to do so, we present a model for the crystallization of a magmatic chamber, coupling the three phenomena ...
Cottin, Jean-Yves, Guy, Bernard, Lakhssassi, Morad, Touboul, Eric   +3 more
core   +4 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Numerical analysis for solidification behaviour of phase change material using MXene nanofluid based thermal energy storage system [PDF]

, 2023
Utkarsh Srivas, Rashmi Rekha Sahoo
openalex   +1 more source

Direct current plasma spraying of mechanofused alumina-steel particles

, 2009
Stainless steel particles (60 $\mu$m in mean diameter) cladded with an alumina shell (2 $\mu$m thick and manufactured by mechanofusion) were sprayed with an Ar-H2 (53-7 slm) d.c. plasma jet (I = 500 A, P = 28 kW, \rho_th = 56 %).
Ageorges, Hélène, Bouneder, Mohamed, Elganaoui, Mohamed, Fauchais, Pierre, Pateyron, Bernard   +4 more
core   +1 more source

Rheological study of sludge of membranes bioreactors for water treatment: protocol, limitations and link with the filtration [PDF]

, 2011
The submerged membranes bio-reactors (sMBR) are more and more visible in the field of waste water treatment. The membrane fouling, that causes a drastic fall of the performances, can be limited by the application of a swarm of bubbles close to the ...
Albasi, Claire, Alliet-Gaubert, Marion, Anne-Archard, Dominique, Cabassud, Corinne, Guigui, Christelle, Günther, Jan, Lorain, Olivier, Schetrite, Sylvie   +7 more
core  

Stimulus-responsive Injectable Polysaccharide Scaffolds for Soft Tissue Engineering Prepared by O/W High Internal Phase Emulsion [PDF]

, 2011
This thesis describes work on the development of several novel stimuli-responsive porous hydrogels prepared from oil-in-water (o/w) high internal phase emulsion (HIPE) as injectable scaffolds for soft tissue engineering.
Zhou, Shengzhong, Zhou, Shengzhong
core   +1 more source