Results 71 to 80 of about 2,059,621 (303)

Unravel melt pool and bubble dynamics during laser powder bed fusion of polyamides using synchrotron X-ray imaging and process simulation

Virtual and Physical Prototyping
Laser powder bed fusion (LPBF) of Polyamide 12 (PA12) using a near-infra-red (NIR) beam is largely unexplored; therefore, the beam-matter interaction, evolution mechanisms of the melt pool and defects remain unclear. Here, we employed a combination of in
Chu Lun Alex Leung, Jabbar Gardy, Mark Isaacs, Shashidhara Marathe, Michał M. Kłosowski, Junji Shinjo, Chinnapat Panwisawas, Peter D. Lee   +7 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Rheological study of sludge of membranes bioreactors for water treatment: protocol, limitations and link with the filtration [PDF]

, 2011
The submerged membranes bio-reactors (sMBR) are more and more visible in the field of waste water treatment. The membrane fouling, that causes a drastic fall of the performances, can be limited by the application of a swarm of bubbles close to the ...
Albasi, Claire, Alliet-Gaubert, Marion, Anne-Archard, Dominique, Cabassud, Corinne, Guigui, Christelle, Günther, Jan, Lorain, Olivier, Schetrite, Sylvie   +7 more
core  

Stimulus-responsive Injectable Polysaccharide Scaffolds for Soft Tissue Engineering Prepared by O/W High Internal Phase Emulsion [PDF]

, 2011
This thesis describes work on the development of several novel stimuli-responsive porous hydrogels prepared from oil-in-water (o/w) high internal phase emulsion (HIPE) as injectable scaffolds for soft tissue engineering.
Zhou, Shengzhong, Zhou, Shengzhong
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Direct current plasma spraying of mechanofused alumina-steel particles

, 2009
Stainless steel particles (60 $\mu$m in mean diameter) cladded with an alumina shell (2 $\mu$m thick and manufactured by mechanofusion) were sprayed with an Ar-H2 (53-7 slm) d.c. plasma jet (I = 500 A, P = 28 kW, \rho_th = 56 %).
Ageorges, Hélène, Bouneder, Mohamed, Elganaoui, Mohamed, Fauchais, Pierre, Pateyron, Bernard   +4 more
core   +1 more source

Tumor growth instability and the onset of invasion

, 2005
Motivated by experimental observations, we develop a mathematical model of chemotactically directed tumor growth. We present an analytical study of the model as well as a numerical one.
A. H. Nayfeh, A. J. Ekstrand, A. J. Ekstrand, A. Wells, A.-L. Barabási, Carmen Molina-París, D. S. Jones, H. M. Byrne, J. A. Sherratt, J. P. Freyer, J. P. Freyer, M. J. Holmes, M. R. Chicoine, M. R. Chicoine, Mario Castro, P. C. Fife, P. Grindrod, R. K. Jain, S. H. Strogatz, S. Koochekpour, Thomas S. Deisboeck   +20 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

One-dimensional solidification of supercooled melts [PDF]

, 2012
In this paper a one-phase supercooled Stefan problem, with a nonlinear relation between the phase change temperature and front velocity, is analysed.
Font Martínez, Francesc, Mittchell, Sara L., Myers, T. G., Universitat Autònoma de Barcelona. Centre de Recerca Matemàtica   +3 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source