Results 131 to 140 of about 17,105 (305)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Solidity Compiler Version Identification on Smart Contract Bytecode
, 2023 Identifying the version of the Solidity compiler used to create an Ethereum contract is a challenging task, especially when the contract bytecode is obfuscated and lacks explicit metadata.
Devasani, Lakshmi Prasanna Katyayani
core
ESBMC-Solidity: An SMT-Based Model Checker for Solidity Smart Contracts
Smart contracts written in Solidity are programs used in blockchain networks, such as Etherium, for performing transactions. However, as with any piece of software, they are prone to errors and may present vulnerabilities, which malicious attackers could
de Lima Filho, Eddie B. +3 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Strong solidity of q-Gaussian algebras
, 2020 In 2011 Avsec showed strong solidity of the q-Gaussian algebras, building upon previous results of Houdayer and Shlyakhtenko, and Ozawa and Popa. In this work we study this result as well as the necessary literature and q-mathematics needed to replicate ...
Wildschut, Guillermo (author)
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Solidity 0.5: when typed does not mean type safe
, 2019 The recent release of Solidity 0.5 introduced a new type to prevent Ether transfers to smart contracts that are not supposed to receive money. Unfortunately, the compiler fails in enforcing the guarantees this type intended to convey, hence the type ...
Silvia Crafa, Matteo Di Pirro
core