Results 101 to 110 of about 4,084,661 (297)

Maximum discharge and probable rainfall at Aiuruoca basin, Minas Gerais State

Revista Ambiente & Água, 2014
Research on rainfall and annual daily maximum discharge rates is essential to support decisions during the design of hydraulic structures. This study tested the adequacy of probability functions to predict the probable rainfall and discharge rates of the
Leandro Campos Pinto, Pedro Luiz Terra Lima, Zélio Resende de Souza   +2 more
doaj   +1 more source

1998 Summer Concert Series Concert III: Unaccompanied Cello Music from Germany, June 10, 1998 [PDF]

, 1998
This is the concert program of the 1998 Summer Concert Series Concert III: Unaccompanied Cello Music from Germany performance on Wednesday, June 10, 1998 at 12:00 p.m., at Marsh Chapel, 735 Commonwealth Avenue. Works performed were Suite No. 3 in C major
School of Music, Boston University
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

String Department Students' Concert, October 26, 1988 [PDF]

, 1988
This is the concert program of the String Department Students' Concert performance on Wednesday, October 26, 1988 at 8:30 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Influência da incorporação de coberturas mortas e da mobilização no comportamento térmico da camada de ar acima de um Solo mediterrâneo pardo [PDF]

, 2010
A aplicação de coberturas mortas (mulches) à superfície do solo ou a simples mobilização deste influenciam directamente o respectivo balanço energético, modificando deste modo o ambiente térmico da camada superficial do solo e o da camada de ar ...
Andrade, José
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Caracterização dos teores naturais de bário em diferentes solos no estado de Santa Catarina

Agropecuária Catarinense
O bário pode estar presente no solo como resultado de processos geológicos naturais ou por atividades antrópicas. O objetivo do trabalho foi avaliar os teores de bário em 34 solos da serra e oeste catarinenses e sua correlação com o pH, matéria orgânica,
Daniely Neckel Rosini, Caroline Aparecida Matias, Betel Cavalcante Lopes, Beatriz Rodrigues Baguinolin Muniz, Fabiele Arruda Delfino, Leticia Visentin Borges, Mari Lucia Campos   +6 more
doaj  

Michael Webster, clarinet and Barry Snyder, piano, February 3, 1988 [PDF]

, 1988
This is the concert program of the Michael Webster, clarinet and Barry Snyder, piano performance on Wednesday, February 3, 1988 at 8::00 p.m., at the Concert Hall, 855 Commonwealth Avenue.
School of Music, Boston University
core