Results 111 to 120 of about 4,084,661 (297)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
ALEA III, The Low C's, April 23, 2014 [PDF]
, 2014 This is the concert program of the ALEA III, The Low C's performance on Wednesday, April 23, 2014 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Telemetric longitudinal measurement of young driver behaviour [PDF]
, 2008 New Zealand is one of the few countries that currently allows teenagers to become solo drivers at 15 ½ years of age. During their first six months of solo driving, these teenagers are 19 times more likely to crash compared to the period of supervised ...
Isler, Robert B., Starkey, Nicola J.
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Kajian Peran Waduk Sebagai Pengendali Kualitas Air Secara Alami
Forum Geografi, 2016 In Indonesia it was identified that there were much of polluted stream flow which cause improper consumed water. One of the rivers which has low of water qualities is Citarum River, West Java.
Agung B. Supangat, Paimin Paimin
doaj
String Department Recital, March 29, 1993 [PDF]
, 1993 This is the concert program of the String Department Recital on Monday, March 29, 1993 at 8:00 p.m., at the Marshall Room, 855 Commonwealth Avenue. Works performed were Andante sostenuto from Violin Concerto No. 1 by Aram Khachaturian, Allegro vivace and
School of Music, Boston University
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Obsession: work by Esther Johnson solo show [PDF]
To coincide with Ways of Looking, a new festival of photography in Bradford, South Square will be presenting artist filmmaker and photographer Esther Johnson’s Analogue Kingdom. This short film is a poetic portrait of Gerald Wells, founder and curator of
Johnson, Esther
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