Results 131 to 140 of about 809,733 (304)

Indicadores de qualidade do solo na avaliação do efeito da arborização de pastagem em Pastoreiro Racional Voisin [PDF]

open access: yes, 2015
Dissertação (mestrado profissional) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Agroecossistemas, Florianópolis, 2015.Apesar da importância da atividade leiteira no Brasil, o uso intensivo e as ...
Bourscheid, César Alexandre
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Vulnerabilidade do solo a poluição por fósforo, cobre e zinco, em áreas sob aplicação de dejetos de suínos [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Ambiental, Florianópolis, 2014No estado de Santa Catarina as propriedades suinícolas utilizam os dejetos líquidos de suínos como única ...
Couto, Rafael da Rosa
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

ANTESEDEN RISK DAN TRUST YANG MEMPENGARUHI SIKAP INDIVIDU TERHADAP NIAT ADOPSI E-BANKING

open access: yesBenefit Jurnal Manajemen dan Bisnis, 2012
The e-banking adoption researches have been conducted with diversity in the approach models in which they found the model diversity so that these are casuistic. This fact becomes an interesting gap research.
Edy Purwo Saputro   +1 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

THE EFFORTS OF AND THE PROBLEMS FACED BY  DINAS KEBUDAYAAN DAN PARIWISATA  (DISBUDPAR) SURAKARTA IN ATTRACTING TOURISTS TO VISIT SOLO CITY [PDF]

open access: yes, 2009
Fina Rantika Sari. 2009. The Efforts of Dinas Kebudayaan dan Pariwisata (DISBUDPAR) Surakarta in  Attracting Tourists to Visit Solo City. English Diploma Program, Faculty of Letters and Fine Arts,  Sebelas Maret University.
Rantika Sari, Fina
core  

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