Results 71 to 80 of about 526 (152)

suppl._mat – Supplemental material for A randomized, double-blind, placebo-controlled, crossover study to evaluate the human abuse liability of solriamfetol, a selective dopamine and norepinephrine reuptake inhibitor

open access: yes, 2018
Supplemental material, suppl._mat for A randomized, double-blind, placebo-controlled, crossover study to evaluate the human abuse liability of solriamfetol, a selective dopamine and norepinephrine reuptake inhibitor by Lawrence P Carter, Jack E ...
Jack E Henningfield (5810291)   +6 more
core   +1 more source

Solriamfetol for treating excessive sleepiness caused by narcolepsy: a Single Technology Appraisal

open access: yes, 2020
This report is a critique of the company submission (CS) to NICE from Jazz Pharmaceuticals on the clinical effectiveness and cost effectiveness of solriamfetol for treating excessive daytime sleepiness caused by narcolepsy.
Lord, Joanne   +6 more
core  

Solriamfetol for treating excessive daytime sleepiness caused by obstructive sleep apnoea: a Single Technology Appraisal

open access: yes, 2020
This report is a critique of the company's submission (CS) to NICE from Jazz Pharmaceuticals on the clinical effectiveness and cost effectiveness of solriamfetol for treating excessive daytime sleepiness caused by obstructive sleep apnoea.
Lord, Joanne   +5 more
core  

SOLRIAMFETOL ON COGNITION IN OBSTRUCTIVE SLEEP APNEA WITH EXCESSIVE DAYTIME SLEEPINESS AND IMPAIRED COGNITION

open access: yes
Introduction: Cognitive impairment is a burdensome symptom in many patients with excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA).
Drake, Christopher   +5 more
core  

Comparative efficacy, safety and benefit/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysis

open access: yes
BACKGROUND: Obstructive sleep apnoea (OSA) is a common chronic respiratory disease associated with a high burden of disabilities related to sleepiness and reduced quality of life.
Lehert, P   +11 more
core   +2 more sources

Effects of solriamfetol on cognition in participants with cognitive impairment associated with excessive daytime sleepiness in obstructive sleep apnea: SHARP study results

open access: yes
Introduction: The SHARP study evaluated whether solriamfetol improves cognitive function in patients with obstructive sleep apnea (OSA) experiencing excessive daytime sleepiness (EDS) and extant impaired cognition.
Bates, J.   +9 more
core  

Drug-induced versus non-pharmacological wakefulness: similar or different states? A whole brain analysis in TRAP2 transgenic mice

open access: yes
A large body of data indicate that the aminergic, cholinergic and hypocretin/orexin neurons are responsible for inducing wakefulness. However, recent data showed that other systems might also play a key role.
Queiroz, Claudio Marcos   +6 more
core   +1 more source

Evaluating pharmacological treatments for excessive daytime sleepiness in obstructive sleep apnea: A comprehensive network meta-analysis and systematic review

open access: yes
Obstructive sleep apnea (OSA) is associated with excessive daytime sleepiness (EDS). Pharmacotherapy offers a potential treatment approach for EDS in OSA patients.
Arunthari, Vichaya   +8 more
core   +1 more source

Results of the Solriamfetol\u27s Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-Controlled Study (SHARP): A Randomized Placebo-Controlled Double-Blind Repeated-Measures Crossover Phase IV Clinical Trial of the Effect of the Wake-Promoting Agent Solriamfetol on Cognitive Function in OSA With Excessive Daytime Sleepiness and Cognitive Impairment

open access: yes
BACKGROUND: OSA causes episodes of fragmented sleep and intermittent hypoxia and leads to excessive daytime sleepiness (EDS). Deficits in cognitive function are a troublesome symptom in patients with OSA and EDS.
Tabuteau, Herriot   +7 more
core   +1 more source

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