Results 211 to 220 of about 1,167,583 (353)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Mutual solubilization of rosiglitazone and ibuprofen: Investigation and mechanistic insight. [PDF]

PLoS One
Gong Y, Liu W.
europepmc   +1 more source

Solubility and dissolution performances of spray-dried solid dispersion of Efavirenz in Soluplus

, 2016
Zênia Maria Maciel Lavra, Davi Pereira de Santana, Maria Inês Ré   +2 more
openalex   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Tuning the Solvation and Solubility Properties of Molecularly Heterogeneous Nonionic Deep Eutectic Solvents via Interface Organization. [PDF]

Langmuir
Sepulveda-Montaño LX, Estrella CN, Skinner AM, Kuroda DG.   +3 more
europepmc   +1 more source

THE MOLECULAR WEIGHT AND SOLUBLE COLLAGEN CONTENT OF FININGS IN RELATION TO ITS FINING POTENTIAL [PDF]

, 1967
A. A. Leach, J. Barrett
openalex   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Accelerating supercritical pharmaceutical formulation via interpretable data-driven prediction of drug solubility. [PDF]

Sci Rep
Khafagy ES, Lila ASA, Pishnamazi M.
europepmc   +1 more source

Loss of Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein α (αSNAP) Induces Epithelial Cell Apoptosis via Down-regulation of Bcl-2 Expression and Disruption of the Golgi

, 2011
Nayden G. Naydenov, Gianni Harris, Bryan N. Brown, Katherine L. Schaefer, Swadesh K. Das, Paul B. Fisher, Andrei I. Ivanov   +6 more
openalex   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source