Results 261 to 270 of about 2,048,035 (343)
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Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs.
Life Science, 2022Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical industries. By some estimation, 70-90% drug candidates in development stage while up-to 40% of the marketed products are poorly soluble which leads to low ...
K. Khan +5 more
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Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates
Advanced Drug Delivery Reviews, 2007Nicholas Blagden
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Henry gas solubility optimization: A novel physics-based algorithm
Future generations computer systems, 2019Several metaheuristic optimization algorithms have been developed to solve the real-world problems recently. This paper proposes a novel metaheuristic algorithm named Henry gas solubility optimization (HGSO), which mimics the behavior governed by Henry’s
Fatma A. Hashim +4 more
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Solubility, solvency, and solubility parameters
Industrial & Engineering Chemistry Product Research and Development, 1985Approche du parametre de solubilite a trois composants afin de predire le degre de solubilisation et la solubilite/insolubilite des ...
John W. Van Dyk +2 more
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Scandinavian Journal of Clinical and Laboratory Investigation, 2011
CD163 is an endocytic receptor for haptoglobin-hemoglobin complexes and is expressed solely on macrophages and monocytes. As a result of ectodomain shedding, the extracellular portion of CD163 circulates in blood as a soluble protein (sCD163) at 0.7-3.9 mg/l in healthy individuals.
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CD163 is an endocytic receptor for haptoglobin-hemoglobin complexes and is expressed solely on macrophages and monocytes. As a result of ectodomain shedding, the extracellular portion of CD163 circulates in blood as a soluble protein (sCD163) at 0.7-3.9 mg/l in healthy individuals.
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Macromolecular Rapid Communications, 2013
AbstractThe thermoresponsive transition behavior of a diblock copolymer consisting of poly(ethylene glycol) methyl ether (mPEG) and poly(N,N‐dimethylaminoethyl methacrylate) (PDMAEMA) in aqueous solutions has been investigated. With a specific composition, the copolymer showed a unique tunable phase transition from no response in acidic media to a ...
Xia, Han +5 more
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AbstractThe thermoresponsive transition behavior of a diblock copolymer consisting of poly(ethylene glycol) methyl ether (mPEG) and poly(N,N‐dimethylaminoethyl methacrylate) (PDMAEMA) in aqueous solutions has been investigated. With a specific composition, the copolymer showed a unique tunable phase transition from no response in acidic media to a ...
Xia, Han +5 more
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Solubility of sparingly-soluble ionizable drugs
Advanced Drug Delivery Reviews, 2007The experimental and computational basis of the pH-dependent measurement of solubility of sparingly-soluble ionizable drugs is reviewed. Recently described compound-sparing (but still accurate) approaches, suitable for application in preclinical development, and appropriate for the analysis of solubility of "problematic" molecules, are critically ...
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2009
Udgivelsesdato: 2008-May-16 ; The neural cell adhesion molecule (NCAM) is a membrane-bound glycoprotein involved in homophilic interactions that facilitate cell-cell adhesion. In addition to a number of membrane-bound isoforms, NCAM also exists in several soluble isoforms that have been identified in cerebrospinal fluid, blood serum, brain tissue, and ...
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Udgivelsesdato: 2008-May-16 ; The neural cell adhesion molecule (NCAM) is a membrane-bound glycoprotein involved in homophilic interactions that facilitate cell-cell adhesion. In addition to a number of membrane-bound isoforms, NCAM also exists in several soluble isoforms that have been identified in cerebrospinal fluid, blood serum, brain tissue, and ...
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p -Soluble Hypercenter and p -Soluble Groups
Algebra ColloquiumLet [Formula: see text] be a subgroup of a finite group [Formula: see text] and [Formula: see text] be a prime. We say [Formula: see text] is [Formula: see text]-[Formula: see text]-normal in [Formula: see text] if there is a subnormal subgroup [Formula: see text] of [Formula: see text] such that [Formula: see text] and [Formula: see text] is ...
Liu, Wentao, Qiao, Shouhong, Su, Ning
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2022
Abstract This chapter covers the basic concepts of solubility. It begins with the relevant thermodynamic expressions and key equations used to solve solubility equilibria. pC-pH diagrams are constructed to represent the conditions under which solids form. Carbonate, sulfide, and oxide/hydroxide minerals are emphasized. Water softening is
Patrick L. Brezonik, William A. Arnold
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Abstract This chapter covers the basic concepts of solubility. It begins with the relevant thermodynamic expressions and key equations used to solve solubility equilibria. pC-pH diagrams are constructed to represent the conditions under which solids form. Carbonate, sulfide, and oxide/hydroxide minerals are emphasized. Water softening is
Patrick L. Brezonik, William A. Arnold
openaire +1 more source