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Solubility of the Least-Soluble Asphaltenes [PDF]

open access: possible, 2007
The key to understanding many asphaltene-related phenomena is a quantitative description of the solubility conditions at which the least-soluble asphaltenes begin to flocculate from a crude oil, often referred to as the onset of flocculation. Models that treat asphaltene flocculation as a liquid–liquid phase separation of large solute molecules ...
Jianxin Wang   +2 more
openaire   +1 more source

Are solubilities and solubility products related?

Journal of Chemical Education, 1966
The relation between solubilities and solubility products is far less intimate than is stated or implied by introductory texts and the ideas and calculations involved are too complex for presentation on the elementary level.
Henry C. Thomas   +2 more
openaire   +2 more sources

Solubility, solvency, and solubility parameters

Industrial & Engineering Chemistry Product Research and Development, 1985
Approche du parametre de solubilite a trois composants afin de predire le degre de solubilisation et la solubilite/insolubilite des ...
Harry L. Frisch   +2 more
openaire   +2 more sources

Solubility of sparingly-soluble ionizable drugs

Advanced Drug Delivery Reviews, 2007
The experimental and computational basis of the pH-dependent measurement of solubility of sparingly-soluble ionizable drugs is reviewed. Recently described compound-sparing (but still accurate) approaches, suitable for application in preclinical development, and appropriate for the analysis of solubility of "problematic" molecules, are critically ...
openaire   +3 more sources

Solubility

2008
Publisher Summary Solubility is one of the most important properties in drug discovery. Insoluble compounds can plague discovery. Solubility problems can intensify during discovery because the molecular characteristics needed for strong binding to the target protein can be deleterious to solubility.
Edward H. Kerns, Li Di
openaire   +3 more sources

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