Results 101 to 110 of about 7,812 (188)

First-in-human trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of zagociguat (CY6463), a CNS-penetrant soluble guanylyl cyclase stimulator. [PDF]

Clin Transl Sci, 2023
van Kraaij SJW, Gal P, Borghans LGJM, Klaassen ES, Dijkstra F, Winrow C, Glasser C, Groeneveld GJ.   +7 more
europepmc   +1 more source

Design and characterization of a soluble fragment of the extracellular ligand-binding domain of the peptide hormone receptor guanylyl cyclase-C [PDF]

, 2008
Thomas Lauber, N. Tidten, Irena Matečko, Markus Zeeb, Paul Rösch, Ute C. Marx   +5 more
openalex   +1 more source

Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. [PDF]

Nat Cardiovasc Res, 2022
Mauersberger C, Sager HB, Wobst J, Dang TA, Lambrecht L, Koplev S, Stroth M, Bettaga N, Schlossmann J, Wunder F, Friebe A, Björkegren JLM, Dietz L, Maas SL, van der Vorst EPC, Sandner P, Soehnlein O, Schunkert H, Kessler T.   +18 more
europepmc   +1 more source

Ligand Selectivity of Soluble Guanylyl Cyclase [PDF]

Journal of Biological Chemistry, 2006
Emil Martin, Vladimir Berka, Elena Bogatenkova, Ferid Murad, Ah-Lim Tsai   +4 more
openaire   +1 more source

Dental Pulp Inflammation Initiates the Occurrence of Mast Cells Expressing the α₁ and β₁ Subunits of Soluble Guanylyl Cyclase. [PDF]

Int J Mol Sci, 2023
Korkmaz Y, Plomann M, Puladi B, Demirbas A, Bloch W, Deschner J.   +5 more
europepmc   +1 more source

Homodimerization of Soluble Guanylyl Cyclase Subunits [PDF]

Journal of Biological Chemistry, 1999
Ulrike Zabel, Christoph Häusler, Monika Weeger, Harald H.H.W. Schmidt   +3 more
openaire   +1 more source

The role of NO in signaling pathway in cardiac ischemic preconditioning against myocardial ischemia-reperfusion injury

Регуляторные исследования и экспертиза лекарственных средств, 2018
Many recent studies have confirmed the effect of NO and that its relative signaling pathway is important for preconditioning of the cardioprotective effect. Mitochondria as a target for the cardioprotective effects of nitric oxide in ischemia-reperfusion
L. M. Danilenko, M. V. Pokrovskiy, T. A. Denysyuk, I. M. Kolesnik, S. A. Alekhin   +4 more
doaj  

Responses in Blood Pressure and Kidney Function to Soluble Guanylyl Cyclase Stimulation or Activation in Normal and Diabetic Rats. [PDF]

Nephron, 2023
Patel R, Fu Y, Khang S, Benardeau AM, Thomson SC, Vallon V.   +5 more
europepmc   +1 more source

Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method [PDF]

, 1990
Peter Humbert, Feraydoon Niroomand, Gabriele FISCHER, Bernd Mayer, Doris Koesling, Klaus‐Dieter Hinsch, Heinrich Gausepohlꝉ, Rainer Frank, Günter Schultz, Eycke Böhme   +9 more
openalex   +1 more source

Gemfibrozil derivatives as activators of soluble guanylyl cyclase - A structure-activity study. [PDF]

Eur J Med Chem, 2021
Gayler KM, Quintana JM, Mattke J, Plunk MA, Kostyo JH, Karunananthan JW, Nguyen H, Shuda M, Ferreira LD, Baker H, Stinchcomb AL, Sharina I, Kane RR, Martin E.   +13 more
europepmc   +1 more source