Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity [PDF]
Mediators of Inflammation, 2020 Objective. To investigate the role of soluble interleukin-2R (sIL-2R) in idiopathic inflammatory myopathies (IIM). Methods. Serum sIL-2R levels were measured in 74 dermatomyositis (DM), 16 immune-mediated necrotizing myopathy (IMNM), 24 rheumatoid ...
Linrong He +6 more
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Soluble IL-2 receptor: a biomarker for assessing myositis activity. [PDF]
Dis Markers, 2014 Objective. To evaluate the clinical significance of serum soluble IL-2R (sIL-2R) in inflammatory myopathies.Methods.Serum sIL-2R and CK levels were determined in 27 patients with IM during periods of disease exacerbation and inactive disease and were compared to 20 healthy controls and 23 controls with noninflammatory elevated CK.
Tournadre A +8 more
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Impact of serum levels of IL-18 and soluble IL-2 receptor on the clinical outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP regimen [PDF]
Future Science OA, 2019 Aim & methods: To assess the impact of pretreatment serum levels of IL-18 and soluble IL-2 receptor (sIL-2R) on the clinical outcome of patients with diffuse large B-cell lymphoma treated with an R-CHOP protocol. Total 73 patients were included. Results:
Hussein M Khaled +4 more
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Implication of serum soluble IL-2 receptor α in type 2 diabetes mellitus. [PDF]
J Diabetes Metab DisordThe aim of this study was to determine the association of serum soluble IL-2 receptor α (sIL-2RA) with T2DM-related characteristics and complications.Serum sIL-2RA levels were determined in 156 T2DM patients, and the association with T2DM-related characteristics and complications was evaluated.Serum sIL-2RA levels were significantly increased in T2DM ...
Zhao B +5 more
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Biological significance of soluble IL-2 receptor [PDF]
Mediators of Inflammation, 1993 A NUMBER of receptors for growth factors and differentiation antigens have been found to be secreted or released by cells. Following mononuclear cell (MNC) activation and interleukin-2 receptor (IL-2R) expression, a soluble form of the Alpha;-chain of IL-
Calogero Caruso +4 more
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The soluble
Immunology, 2023 AbstractThe pleiotropic cytokine interleukin‐2 (IL‐2) is an integral regulator of healthy and pathological immune responses, with the most important role in regulating the homeostasis of regulatory T cells. IL‐2 signalling involves three distinct receptors: The IL‐2 receptor α (IL‐2Rα/CD25), IL‐2Rβ, and IL‐2Rγ/γc.
Juliane Lokau +2 more
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Soluble IL-2 receptor in rheumatoid arthritis. Correlation with disease activity, IL-1 and IL-2 inhibition. [PDF]
The Journal of Immunology, 1988 Abstract An ELISA was used to measure soluble IL-2R (sIL-2R) in the sera and synovial fluids of patients with rheumatic diseases. Patients with rheumatoid arthritis had raised levels of sIL-2R both in their sera and in their synovial fluid compared to patients with osteoarthritis and age-matched healthy controls.
J A, Symons +3 more
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Soluble IL-2 receptor levels in patients with Graves'ophthalmopathy
Clinical and Experimental Immunology, 1992 SUMMARYIn various autoimmune diseases circulating levels of soluble 1L-2 receptor (sIL-2R) seem to be related to disease activity. Because reliable parameters of disease activity in Graves' ophthalmopathy are lacking, we measured sIL-2R levels in 47 patients with this disorder, The patients had Graves' disease, but no other immune-mediated diseases ...
Prummel, M. F. +4 more
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Soluble IL-2 receptor levels support diagnosis of sarcoidosis-like reaction in melanoma patients on immunotherapy - a diagnostic algorithm based on a single center retrospective study. [PDF]
J Dtsch Dermatol GesGussek P +3 more
europepmc +3 more sources
Soluble interleukin-2 receptor in pediatric patients investigated for hemophagocytic lymphohistiocytosis: A single-center, 10-year-long experience [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2023 Introduction/Objective Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition characterized by fever, splenomegaly, and cytopenias.
Janković Srđa +5 more
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