Results 181 to 190 of about 460,443 (348)

Serum levels of soluble IL‐2 receptor, IL‐4 and IgE‐binding factors in childhood allergic diseases

Clinical and Experimental Immunology, 1991
T. Matsumoto, T. Miike, K. Yamaguchi, M. Murakami, T. Kawabe, J. Yodoi   +5 more
semanticscholar   +1 more source

Distinct Network Morphologies from In Situ Polymerization of Microtubules in Giant Polymer‐Lipid Hybrid Vesicles

Advanced Biology, Volume 9, Issue 5, May 2025.
The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres, Mousumi Akter, Cecilie Ryberg, Brigitte Städler, Allen P. Liu   +4 more
wiley   +1 more source

Induction of circulating and erythrocyte-bound IL-8 by IL-2 immunotherapy and suppression of its in vitro production by IL-1 receptor antagonist and soluble tumor necrosis factor receptor (p75) chimera. [PDF]

, 1993
Herbert Tilg, Leland Shapiro, M.B. Atkins, Charles A. Dinarello, J W Mier   +4 more
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Mechanical Loading of Osteocytes via Oscillatory Fluid Flow Regulates Early‐Stage PC‐3 Prostate Cancer Metastasis to Bone

Advanced Biology, Volume 9, Issue 4, April 2025.
In this study, the authors show that osteocytes, mechanosensing cells embedded within bone, can indeed regulate prostate cancer cell extravasation through a blood vessel using a physiologically relevant tissue model. Specifically, it is shown that osteocytes modulate the expression of blood vessel cell adhesion molecules, affecting the frequency at ...
Kimberly Seaman, Chun‐Yu Lin, Xin Song, Amel Sassi, William W. Du, Burton Yang, Yu Sun, Lidan You   +7 more
wiley   +1 more source

Predicting novel pharmacological activities of compounds using PubChem IDs and machine learning (CID-SID ML model) [PDF]

arXiv
Significance and Object: The proposed methodology aims to provide time- and cost-effective approach for the early stage in drug discovery. The machine learning models developed in this study used only the identification numbers provided by PubChem.
arxiv  

Perioperative serum levels of tumour‐necrosis‐factor alpha (TNF‐α), IL‐1β, IL‐6, IL‐10 and soluble IL‐2 receptor in patients undergoing cardiac surgery with cardiopulmonary bypass without and with correction for haemodilution

Clinical and Experimental Immunology, 1999
A. Roth-Isigkeit, T. v.Borstel, M. Seyfarth, P. Schmucker   +3 more
semanticscholar   +1 more source

Soluble interleukin-2 (IL-2) receptor expression in patients with myelodysplastic syndromes is induced by granulocyte-macrophage colony- stimulating factor and IL-3 [letter; comment] [PDF]

, 1991
H. Zwierzina, Manfred Herold, D. Geißler, Susanne Schöllenberger, F. Schmalzl   +4 more
openalex   +1 more source

Electrospinning Technology, Machine Learning, and Control Approaches: A Review

Advanced Engineering Materials, Volume 27, Issue 7, April 2025.
Electrospinning produces micro‐ and nanoscale fibers, holding great promise in biomedical engineering. Industrial adoption faces challenges in controlling fiber properties, reproducibility, and scalability. This review explores electrospinning techniques, modeling, and machine learning for process optimization.
Arya Shabani, Gorkem Anil Al, Nael Berri, Bernardo Castro‐Dominguez, Hannah S. Leese, Uriel Martinez‐Hernandez   +5 more
wiley   +1 more source

PepTune: De Novo Generation of Therapeutic Peptides with Multi-Objective-Guided Discrete Diffusion [PDF]

arXiv
Peptide therapeutics, a major class of medicines, have achieved remarkable success across diseases such as diabetes and cancer, with landmark examples such as GLP-1 receptor agonists revolutionizing the treatment of type-2 diabetes and obesity. Despite their success, designing peptides that satisfy multiple conflicting objectives, such as target ...
arxiv