Biological significance of soluble IL-2 receptor [PDF]
Mediators of Inflammation, 1993 A NUMBER of receptors for growth factors and differentiation antigens have been found to be secreted or released by cells. Following mononuclear cell (MNC) activation and interleukin-2 receptor (IL-2R) expression, a soluble form of the Alpha;-chain of IL-
Calogero Caruso +4 more
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On the Role of sIL-2R Measurements in Rheumatoid Arthritis and Cancers [PDF]
Mediators of Inflammation, 2005 A soluble IL-2 receptor (sIL-2R) is a circulating form of a membrane receptor localized on lymphoid and some cancer cells. The biological function of sIL-2R has not been completely understood.
Anna Maria Witkowska
doaj +4 more sources
Serum levels of soluble IL-2 receptor, IL-12, IL-18, and IFN-γ in patients with acute graft-versus-host disease after allogeneic bone marrow transplantation [PDF]
, 2000 Background: Acute graft-versus-host disease still represents the major factor that limits successful allogeneic bone marrow transplantation. Cytokines released by type 1 T-helper cells are thought to play a pivotal role in acute graft-versus-host disease.
Hiroyuki Nakamura +12 more
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Elevated plasma levels of interleukin‐2 and soluble il‐2 receptor in ischemic heart disease [PDF]
Clinical Cardiology, 2001 Alan D. Simon +4 more
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Identification of a soluble IL-2 receptor beta-chain from human lymphoid cell line cells. [PDF]
Journal of Immunology, 1990 A clone was isolated from the human lymphoid cell line YT that displayed IL-2R beta, and was found to express much higher levels of IL-2R beta than the original cells.
Mitsuo Honda +4 more
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Soluble IL-2 receptor in AIDS. Correlation of its serum level with the classification of HIV-induced diseases and its characterization. [PDF]
Journal of Immunology, 1989 By using a fluorescence sandwich ELISA, elevated IL-2R levels were detected in the sera from both HIV-infected hemophiliacs and other HIV-infected patients.
Mitsuo Honda +7 more
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Soluble IL-2 receptor: a biomarker for assessing myositis activity. [PDF]
Dis Markers, 2014 Objective. To evaluate the clinical significance of serum soluble IL-2R (sIL-2R) in inflammatory myopathies. Methods. Serum sIL-2R and CK levels were determined in 27 patients with IM during periods of disease exacerbation and inactive disease and were ...
Tournadre A +8 more
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Serum soluble IL-2 receptor as a tumor marker in patients with hairy cell leukemia [PDF]
Blood, 1988 Activated T cells synthesize and express a cell membrane-bound receptor for interleukin-2 (IL-2) and have recently been shown to secrete a soluble form of the same receptor.
RG Steis +6 more
semanticscholar +3 more sources
The significance of serum soluble IL-2 receptor as a marker for active visceral leishmaniasis in Sicilian patients [PDF]
Clinical and Experimental Immunology, 1992 G. Vitale +8 more
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Soluble IL-2 receptor levels in serum from blood donors seropositive for HIV. [PDF]
Journal of Immunology, 1988 Serum levels of soluble IL-2R (sIL-2R) were measured in blood donors seropositive for HIV. Approximately one-half (53/101) of these seropositive donors exhibited increased serum sIL-2R levels compared with seronegative controls (n = 65).
Harry E. Prince +2 more
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