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IL-6/IL-12 superfamily of cytokines and regulatory lymphocytes play critical roles in the etiology and suppression of CNS autoimmune diseases. [PDF]
Yadav MK, Singh SP, Egwuagu CE.
europepmc +1 more source
MIXED LYMPHOCYTE REACTION-INDUCED RELEASE OF SOLUBLE IL-2 RECEPTOR
We studied the release of soluble interleukin 2 receptor (sIL-2R) by PBMC in mixed lymphocyte reaction (MLR) in order to clarify the significance of high plasma levels of sIL-2R in transplant patients undergoing rejection. Levels of sIL-2R were shown to increase progressively after the first day of the MLR and reached their peak on day 5.
Nete Hornung+4 more
semanticscholar +5 more sources
Soluble IL-2 receptor levels in serum from blood donors seropositive for HIV. [PDF]
Abstract Serum levels of soluble IL-2R (sIL-2R) were measured in blood donors seropositive for HIV. Approximately one-half (53/101) of these seropositive donors exhibited increased serum sIL-2R levels compared with seronegative controls (n = 65).
H E, Prince, S, Kleinman, A E, Williams
semanticscholar +4 more sources
Chitotriosidase and soluble IL‐2 receptor: Comparison of two markers of sarcoidosis severity
Sarcoidosis is a multisystemic granulomatous disease with an unpredictable clinical course characterized by accumulation of activated proliferating T lymphocytes and mononuclear phagocytes in affected organs.The aims of this study were to describe the clinical, radiological and immunological features of a population of sarcoidosis patients followed at ...
BARGAGLI, E.+7 more
openaire +5 more sources
Serum-Soluble IL-2 Receptor and IL-6 Levels in Patients with Melanoma [PDF]
Elevated soluble IL-2 receptor (sIL-2R) and IL-6 serum concentrations have been reported as adverse prognostic factors in several types of cancer. In order to determine whether these factors are predictive of metastatic progression in melanoma, sIL-2R and IL-6 levels were measured in sera from 172 patients with melanoma and 60 in healthy controls. Mean
I. Bilbao+8 more
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Abstract An ELISA was used to measure soluble IL-2R (sIL-2R) in the sera and synovial fluids of patients with rheumatic diseases. Patients with rheumatoid arthritis had raised levels of sIL-2R both in their sera and in their synovial fluid compared to patients with osteoarthritis and age-matched healthy controls.
J A, Symons+3 more
openaire +3 more sources
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Variations in serum soluble IL‐2 receptor concentration
Pediatric Allergy and Immunology, 1994Soluble interleukin‐2 receptor (sIL‐2R) concentrations were measured in the sera of 18 healthy adult volunteers, 40 healthy children aged 5 months ‐ 16 years 8 months and cord blood from 10 babies, using two commercially available ELISA kits (T‐cell Sciences and Serotec).
Jane Warner+3 more
openaire +4 more sources
Soluble IL-2 receptor as an agent of serum-mediated suppression in human visceral leishmaniasis.
The Journal of Immunology, 1991Abstract In visceral leishmaniasis (VL), patient's lymphocytes are not activated by leishmania Ag stimulation, and their sera exhibit a potent nonspecific suppressive effect on the responses of normal lymphocytes. Sera were obtained from 33 VL patients, eight patients with subclinical VL, and from 27 normal volunteers.
M, Barral-Netto+7 more
openaire +3 more sources