Results 21 to 30 of about 460,443 (348)

The soluble IL‐2 receptor α/CD25 as a modulator of IL‐2 function

Immunology, 2023
The pleiotropic cytokine interleukin‐2 (IL‐2) is an integral regulator of healthy and pathological immune responses, with the most important role in regulating the homeostasis of regulatory T cells.
J. Lokau, Lynn M Petasch, Christoph Garbers   +2 more
semanticscholar   +1 more source

Different lymphoid cell populations produce varied levels of neopterin, β2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, interferon-gamma or tumour necrosis factor-alpha [PDF]

Clinical and Experimental Immunology, 1992
Bo Hofmann, H Z Bass, P Nishanian, Mohamed Faisal, Robert A. Figlin, Gregory Sarna, J. L. Fahey   +6 more
openalex   +2 more sources

Predictive Value of Serum Biomarkers for Response of Limited-Stage AIDS-Associated Kaposi Sarcoma to Antiretroviral Therapy With or Without Concomitant Chemotherapy in Resource-Limited Settings [PDF]

, 2023
BackgroundGuidelines for limited-stage human immunodeficiency virus-associated Kaposi sarcoma (AIDS/KS) recommend antiretroviral therapy (ART) as initial treatment.
Borok, Margaret, Bukuru, Aggrey, Busakhala, Naftali, Campbell, Thomas B, Chang, Di, Epeldegui, Marta, Godfrey, Catherine, Hoagland, Brenda, Hosseinipour, Mina C, Kang, Minhee, Kanyama, Cecilia, Krown, Susan E, Langat, Deborah, Lee, Jeannette, Magpantay, Larry I, Martínez-Maza, Otoniel, Mngqibisa, Rosie, Mwelase, Noluthando, Nyirenda, Mulinda, Samaneka, Wadzanai, team, for the A5264 AMC-067   +20 more
core   +1 more source

Elevated Concentrations of Soluble IL-2 Receptor in both Bronchoalveolar Lavage Fluid and Serum in a Patient with BOOP

Tohoku journal of experimental medicine, 2003
Activated soluble IL-2 receptor (sIL-2R) levels are elevated in a variety of diseases associated with T-cell activation. There are no reports of sIL-2R elevations in broncholitis obliterans organizing pneumonia/cryptogenic organizing pneumonia (BOOP/COP),
Osamu Matsuno, Fumiko Okubo, Kazuhiro Masutomo, Fumio Yoshida, Tosiyuki Okubo, Eishi Miyazaki, Tosihide Kumamoto   +6 more
openalex   +3 more sources

The central role of IL-33/IL-1RL1 pathway in asthma:From pathogenesis to intervention [PDF]

, 2021
Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor, Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma.
Hesse, L, Ketelaar, M E, Koppelman, G H, Nawijn, M C, Saikumar Jayalatha, A K   +4 more
core   +1 more source

Circulating levels of IL-1beta, IL-6 and soluble IL-2 receptor in polymyalgia rheumatica and giant cell arteritis and rheumatoid arthritis [PDF]

British Journal of Rheumatology, 1998
G. Pountain, B L Hazleman, Tim E. Cawston   +2 more
openalex   +2 more sources

Circulating Levels of Cytokines and Their Endogenous Modulators in Patients With Mild to Severe Congestive Heart Failure Due to Coronary Artery Disease or Hypertension [PDF]

, 1996
Objectives. This study sought to determine the circulating levels of cytokines and their respective endogenous modulators in patients with congestive heart failure of variable severity.Background.
BERMAN, JOAN W, FANELLI, RAFFAELE, LEE, PAUL, LEJEMTEL, THIERRY H, LOPERFIDO, FRANCESCO, TESTA, MARCO, YEH, MICHAEL   +6 more
core   +1 more source

Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells

Biochemistry and Biophysics Reports, 2016
Type 2 innate lymphoid cells (ILC2) in lungs produce interleukin (IL)-5 and IL-13 in response to IL-33 and may contribute to the development of allergic diseases such as asthma.
Hiroko Hayakawa, Morisada Hayakawa, Shin-ichi Tominaga   +2 more
doaj   +1 more source

SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells.

PLoS Pathogens, 2020
Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2 infection, although the mechanism for initiation of a hyper-inflammatory response, and multi-organ damage from viral infection is poorly understood.
Tapas Patra, Keith Meyer, Lizzie Geerling, T Scott Isbell, Daniel F Hoft, James Brien, Amelia K Pinto, Ratna B Ray, Ranjit Ray   +8 more
doaj   +1 more source

Soluble IL-2 receptor in rheumatoid arthritis. Correlation with disease activity, IL-1 and IL-2 inhibition.

Journal of Immunology, 1988
An ELISA was used to measure soluble IL-2R (sIL-2R) in the sera and synovial fluids of patients with rheumatic diseases. Patients with rheumatoid arthritis had raised levels of sIL-2R both in their sera and in their synovial fluid compared to patients ...
J. Symons, N. Wood, F. Giovine, G. Duff
semanticscholar   +1 more source