Results 301 to 310 of about 391,404 (343)

Serum-Soluble IL-2 Receptor and IL-6 Levels in Patients with Melanoma

Oncology, 1997
Elevated soluble IL-2 receptor (sIL-2R) and IL-6 serum concentrations have been reported as adverse prognostic factors in several types of cancer. In order to determine whether these factors are predictive of metastatic progression in melanoma, sIL-2R and IL-6 levels were measured in sera from 172 patients with melanoma and 60 in healthy controls. Mean
M D, Boyano, M D, García-Vázquez, J, Gardeazabal, A, García de Galdeano, I, Smith-Zubiaga, M L, Cañavate, J A, Raton, I, Bilbao, J L, Díaz-Pérez   +8 more
openaire   +2 more sources

[Soluble IL-2 receptor levels in rheumatic diseases].

Ryumachi. [Rheumatism], 1993
We measured soluble interleukin-2 receptors (sIL-2R) in plasma and/or joint fluid (JF) from patients with rheumatoid arthritis (RA: 16 patients), Sjögren's syndrome (SS: 24 patients) and Behçet's disease (BD: 23 patients). Plasma sIL-2R levels were significantly higher in RA patients (956 +/- 994 U/ml, p < 0.01) and SS patients (1025 +/- 1112 U/ml, p <
M, Takaya, Y, Ichikawa, H, Shimizu, M, Uchiyama, J, Moriuchi, S, Arimori   +5 more
openaire   +1 more source

Increased soluble IL-2 receptor in serum of patients with systemic lupus erythematosus

Clinical Rheumatology, 1993
We estimated the concentration of soluble IL-2R (sIL-2R) in the serum of patients with systemic lupus erythematosus (SLE) and examined the relationship between the serum levels of sIL-2R and clinical features or laboratory data. We found that elevated levels of sIL-2R were present in the serum of SLE patients with discoid rash, and sIL-2R ...
S. Sawada, H. Hashimoto, S. Iijma, Y. Tokano, Y. Matsukawa, M. Takei, H. Ishikawa, H. Kang, K. Tomura, K. Mitamura, S. Hashimoto, T. Obara   +11 more
openaire   +2 more sources

Soluble interleukin 2 receptors abrogate IL-2 induced activation of peripheral mononuclear cells

Cytokine, 1994
Soluble interleukin 2 receptors (sIL-2R) exert a potential role in immunoregulation. We investigated the in vitro effects of sIL-2R on several interleukin 2 (IL-2)-dependent cellular events. Cytotoxicity of human rIL-2-stimulated PBMC against K562 and Daudi was correlated inversely to the concentration of sIL-2R in the culture medium during rIL-2 ...
U, Zorn, I, Dallmann, J, Grosse, H, Kirchner, H, Poliwoda, J, Atzpodien   +5 more
openaire   +2 more sources

Circulating Soluble IL-2 Receptor Levels are Low in Patients with Hypothyroid Autoimmune Thyroiditis

Hormone and Metabolic Research, 1994
In hypothyroid patients serum soluble IL-2 receptor levels showed scattered and conflicting results. In our report we studied circulating soluble interleukin 2 receptors in 22 patients with hypothyroid autoimmune thyroiditis before L-thyroxine treatment and when the patients became euthyroid.
LOVISELLI, ANDREA, CALIA MA, MURENU S, MOSSA P, CAMBOSU MA, CARADONNA A.   +5 more
openaire   +3 more sources

Anti-IL-2 receptor monoclonal antibody AMT-13 increases soluble IL-2 receptor levels in vivo.

Immunology, 1989
A rat anti-interleukin-2 receptor (IL-2R) monoclonal antibody (mAb), AMT-13, has been shown to prolong cardiac allograft survival in mice. However, neither the mechanism of its immunosuppressive action, nor its other in vivo effects, have been studied extensively.
K, Burkhardt, T E, Mandel, T, Diamantstein, M S, Loughnan   +3 more
openaire   +1 more source

IL-2 responsiveness of lectin-induced lymphoblasts: Soluble IL-2 receptor release and differential in vitro effects of immunosuppressants

International Journal of Immunopharmacology, 1992
We examined the mode of action of different immunosuppressants on the responsiveness of phytohemagglutinin (PHA)-induced lymphoblasts further stimulated by recombinant interleukin-2 (rIL-2). The stimulation of PHA blasts with rIL-2 resulted in an enhancement of tritiated thymidine ([3H]TdR) incorporation and of soluble interleukin-2 receptor (sIL-2R ...
N, Hornung, J, Raskova, K, Raska, D, Degiannis   +3 more
openaire   +2 more sources

[A case of tuberculosis pleuritis with high serum soluble IL-2 receptor].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004
A 56-year-old man was admitted to our hospital because of bilateral pleural effusion. Computed tomography revealed solitary mediastinal lymphadenopathy, splenomegaly and a small amount of ascites. No lung parenchymal lesion was seen. Although lymphocyte predominance without atypia and a high adenocine deaminase concentration in the pleural fluid were ...
Yuya, Fujiwara, Naotsugu, Takahashi, Hiroshi, Koto, Hiroko, Nogami, Kinji, Yokota, Terufumi, Shimoda, Shunsuke, Shoji, Sankei, Nishima, Chiharu, Kubo   +8 more
openaire   +2 more sources

[Serum soluble IL-2 receptor level in patients with sarcoidosis].

Nihon Kyobu Shikkan Gakkai zasshi, 1991
Serum levels of soluble IL-2 receptors (sIL-2R) by an ELISA method in 28 patients with sarcoidosis and 16 healthy controls were studied, and the source of sIL-2R was further examined. sIL-2R in serum was significantly higher in sarcoidosis than in controls.
Y, Ina, K, Takada, M, Noda, T, Satou, H, Hashiba, A, Miyachi, S, Ito, N, Iijima, M, Yamamoto   +8 more
openaire   +1 more source

[Soluble IL-2 receptor levels in patients with Graves' ophthalmopathy].

Yan ke xue bao = Eye science, 2004
Soluble interleukin-2 receptor (sIL-2R) levels in sera with Graves' ophthmopathy was investigated for its relationship to the clinical manifestations and therapeutic effects.sIL-2R levels were measured in sera of 41 patients with Graves' ophthalmopathy which had not yet received specific treatment for their ophthalmopathy and euthyroid during the ...
H, Yang, Z, Wu, X, Huang, C, Xie, P, Yang   +4 more
openaire   +1 more source