Plasma cytokine profiles in HIV-1 infected patients developing neuropathic symptoms shortly after commencing antiretroviral therapy: a case-control study [PDF]
, 2014 Background In patients infected with human immunodeficiency virus 1 (HIV-1) neuropathic symptoms may develop within weeks of starting combination antiretroviral therapy (cART).
Heckmann, JM +3 more
core +1 more source
A Magnetic Bead-Based Sensor for the Quantification of Multiple Prostate Cancer Biomarkers. [PDF]
, 2015 Novel biomarker assays and upgraded analytical tools are urgently needed to accurately discriminate benign prostatic hypertrophy (BPH) from prostate cancer (CaP).
Brooks, James D +7 more
core +7 more sources
Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages [PDF]
, 2010 Background Interleukin-33 is a member of the IL-1 cytokine family whose functions are mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have been explored in mouse macrophages but little is known about the effect of IL-33 ...
Das, Anuk +7 more
core +5 more sources
Study of dose-dependent combination immunotherapy using engineered T cells and IL-2 in cervical cancer [PDF]
, 2020 Adoptive T cell based immunotherapy is gaining significant traction in cancer treatment. Despite its limited success, so far, in treating solid cancers, it is increasingly successful, demonstrating to have a broader therapeutic potential. In this paper we develop a mathematical model to study the efficacy of engineered T cell receptor (TCR) T cell ...
arxiv +1 more source
Soluble gC1qR is an autocrine signal that induces B1R expression on endothelial cells [PDF]
, 2013 Bradykinin (BK) is one of the most potent vasodilator agonists known and belongs to the kinin family of proinflammatory peptides. BK induces its activity via two G protein-coupled receptors: BK receptor 1 (B1R) and BK receptor 2.
David, H +10 more
core +2 more sources
The riddle of the plant vacuolar sorting receptors [PDF]
Protoplasma 226 (12/2005) 103-8, 2006 Proteins synthesized on membrane-bound ribosomes are sorted at the Golgi apparatus level for delivery to various cellular destinations: the plasma membrane or the extracellular space, and the lytic vacuole or lysosome. Sorting involves the assembly of vesicles, which preferentially package soluble proteins with a common destination.
arxiv +1 more source
Mediators of Inflammation, 2009 We determined the role of interleukin-1β (IL-1β) signaling on tumor necrosis factor alpha-induced (TNF-α) lung neutrophil influx as well as neutrophil chemoattractant macrophage inflammatory protein (MIP-2) and KC and soluble TNF-α receptor (TNFR) levels
Sara Saperstein +5 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 1987 Anti-idiotypic (anti-Id) T cells from schistosomiasis patients or former patients proliferate upon exposure to polyclonal or monoclonal anti-soluble egg antigen (SEA) antibodies.
D. G. Colley +7 more
doaj +1 more source
Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals. [PDF]
, 2015 BackgroundClinically significant dysregulation of the insulin-like growth factor (IGF) family proteins occurs in HIV-infected individuals, but the details including whether the deficiencies in IGFs contribute to CNS dysfunction are unknown.MethodsWe ...
Choi, Namjong +4 more
core +2 more sources
Clinical Value of Neopterin In Infectious Complications
Pteridines, 1999 Neopterin, a pteridine intermediate metabolite in the biopterine synthetic pathway, is synthesized and secreted by monocyte/macrophages upon stimulation, mainly by gamma-interferon by activated T cells.
Iwagaki Hiromi +5 more
doaj +1 more source